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MTF1 antibody (C-Term)
MTF1
Reactivity: Human, Mouse, Rat, Dog, Cow
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MTF1 Antibody
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Target
See all MTF1 Antibodies
MTF1
(Metal-Regulatory Transcription Factor 1 (MTF1))
Binding Specificity
All epitopes for MTF1 antibodies
C-Term
Reactivity
All reactivities for MTF1 antibodies
Human, Mouse, Rat, Dog, Cow
Host
All hosts for MTF1 antibodies
Rabbit
Clonality
All clonalities for MTF1 antibodies
Polyclonal
Conjugate
All conjugates for MTF1 antibodies
This MTF1 antibody is un-conjugated
Application
All applications for MTF1 antibodies
Western Blotting (WB)
Sequence
QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
Cross-Reactivity (Details)
Species reactivity (expected):Mouse (100 %), Rat (100 %), Dog (100 %), Bovine (100 %), Horse (100 %), Guinea Pig (92 %), Rabbit (92 %). Species reactivity (tested):Human.
Purification
Purified on Protein A affinity column.
Immunogen
The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1.
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Add 100 μL of distilled water to a final concentration of 1 mg/mL
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
Expiry Date
12 months
Target Details for MTF1
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Target
MTF1
(Metal-Regulatory Transcription Factor 1 (MTF1))
Alternative Name
MTF1 (MTF1 Products )
Synonyms
MTF-1 antibody, MTF1 antibody, mtf1 antibody, MGC86485 antibody, Thyls antibody, ZRF antibody, metal regulatory transcription factor 1 antibody, metal-regulatory transcription factor 1 antibody, metal-regulatory transcription factor 1 L homeolog antibody, metal response element binding transcription factor 1 antibody, MTF1 antibody, mtf1 antibody, mtf1.L antibody, Mtf1 antibody
Background
The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.Synonyms: MRE-binding transcription factor, Metal regulatory transcription factor 1, Transcription factor MTF-1
Molecular Weight
81 kDa (753 amino acids)
Gene ID
4520
NCBI Accession
NP_005946
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