CMV gB antibody (FITC)
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- Target
- CMV gB
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Reactivity
- Cytomegalovirus (CMV)
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- FITC
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Application
- Immunofluorescence (IF)
- Specificity
- This antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. It reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be neutralizing.
- Purification
- Affinity chromatography on Protein G
- Immunogen
- Human CMV extracts
- Clone
- HCMV37
- Isotype
- IgG2a
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- Application Notes
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Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,1 mg/mL
- Buffer
- PBS, pH 7.2, 0.09 % Sodium Azide, 1 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CMV gB
- Target Type
- Viral Protein
- Background
- Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100 kDa.Synonyms: Cytomegalovirus, Glycoprotein B, HCMV, HHV5, UL55
- Gene ID
- 1487750
- NCBI Accession
- NP_039989
- UniProt
- P06473
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