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CD25 antibody
IL2RA
Reactivity: Human
FACS, Func
Host: Mouse
Monoclonal
B-B10
unconjugated
Product Details anti-CD25 Antibody
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Target
See all CD25 (IL2RA) Antibodies
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Reactivity
All reactivities for CD25 antibodies
Human
Host
All hosts for CD25 antibodies
Mouse
Clonality
All clonalities for CD25 antibodies
Monoclonal
Conjugate
All conjugates for CD25 antibodies
This CD25 antibody is un-conjugated
Application
All applications for CD25 antibodies
Flow Cytometry (FACS), Functional Studies (Func)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ion Exchange Chromatography.
Sterility
0.22 μm filtered
Immunogen
PHA activated T cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
Clone
B-B10
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
Preservative
Without preservative
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for CD25
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Target
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Alternative Name
CD25 / IL2RA (IL2RA Products )
Synonyms
CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
Background
IL-2R (T-cell growth factor receptor) consists of a chain of 55 kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or beta chain. IL-2RA is over-expressed on the surface of activated Tcells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages. CD25 Molecule alone appears to function as a low affinity receptor and associates wtih CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55
Gene ID
3559
NCBI Accession
NP_000408
UniProt
P01589
Pathways
JAK-STAT Signaling , Growth Factor Binding , Activated T Cell Proliferation
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