CD1b antibody
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- Target See all CD1b (CD1B) Antibodies
- CD1b (CD1B)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD1b antibody is un-conjugated
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Application
- Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
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100-1A5 binds with CD1b which is a 45 kDa membrane glycoprotein expressed together with beta-2 Microglobulin. This antibody reacts with cortical thymocytes, Langerhans cells interdigitating cells and with pyramidal cells in the brain. It can be applied for characterization of leukemia's and lymphomas.
Cellular Localization: Cell membrane and cytoplasm. - Purification
- Purified
- Clone
- 100-1A5
- Isotype
- IgM
- Top Product
- Discover our top product CD1B Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CD1b (CD1B)
- Alternative Name
- CD1b (CD1B Products)
- Synonyms
- CD1 antibody, CD1A antibody, R1 antibody, CD1B3 antibody, CD1B antibody, CD1-b antibody, CD1b molecule antibody, T-cell surface glycoprotein CD1b-3 antibody, CD1b1 molecule antibody, T-cell surface glycoprotein CD1b1 antibody, CD1B antibody, LOC443423 antibody, CD1B1 antibody, LOC100720602 antibody
- Background
- CD1b which is associated with β2 microglobulin (1) is expressed on cortical thymocytes (moderate), Langerhans cells, interdigitating cells and brain pyramidal cells (1). It is up-regulated in peripheral neuropathy and inflammatory diseases (2,3). CD1b is the member of CD1 family. At least five CD1 genes (CD1a, b, c, d, and e) are identified (1). Unlike other members in CD1 family which have multiple splicing patterns, CD1b only revealed a single membrane RNA product (1). CD1 proteins including CD1b have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation (4)Synonyms: T-cell surface glycoprotein CD1b
- Molecular Weight
- 45 kDa
- Gene ID
- 910
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