CCR7 antibody

Catalog No. ABIN1105995

Product Details anti-CCR7 Antibody

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR7 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Sequence: YIGDNTTVDY TLFESLC

Specificity: This antibody reacts with human CD197/CCR7.

Purification: Protein A agarose

Immunogen: Human CCR7 peptide

Clone: 6B3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol and 0.5 M NaCl, pH 7.2. Contains no preservative.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Alternative Name: CD197 / CCR7 (CCR7 Products)

Background: CD197/CCR7, also known as EBI1, is a member of the 7-transmembrane G-protein coupled chemokine receptor family. It is expressed on T, B, and mature dendritic cells and is up-regulated in CD4+ T cells in response to infection with human herpesvirus (HHV)-6 and HHV-7. It is reported that increased CCR7 expression plays a role in lymphoid organ infiltration of adult T-cell leukemia (ATL) cells.Synonyms: BLR2, C-C CKR-7, C-C chemokine receptor type 7, CC-CKR-7, CCR-7, CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1, EVI1, MIP-3 beta receptor

Gene ID: 1236

NCBI Accession: NP_001829

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process