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CCNDBP1 antibody (Internal Region)
CCNDBP1
Reactivity: Human, Cow, Dog, Pig
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-CCNDBP1 Antibody
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Target
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CCNDBP1
(Cyclin D-Type Binding-Protein 1 (CCNDBP1))
Binding Specificity
All epitopes for CCNDBP1 antibodies
AA 322-333, Internal Region
Reactivity
All reactivities for CCNDBP1 antibodies
Human, Cow, Dog, Pig
Host
All hosts for CCNDBP1 antibodies
Goat
Clonality
All clonalities for CCNDBP1 antibodies
Polyclonal
Conjugate
All conjugates for CCNDBP1 antibodies
This CCNDBP1 antibody is un-conjugated
Application
All applications for CCNDBP1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-TKASHVTPQP ED
Specificity
This antibody recognizes CCNDBP1.
Cross-Reactivity (Details)
Species reactivity (expected):Canine (Dog), Bovine, Porcine. Species reactivity (tested):Human.
Purification
Affinity Chromatography
Immunogen
Synthetic peptide (C-TKASHVTPQPED) from the internal region (near C-Terminus) of Human CCNDBP1 (NP_036274.3). Genename: CCNDBP1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CCNDBP1
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Target
CCNDBP1
(Cyclin D-Type Binding-Protein 1 (CCNDBP1))
Alternative Name
CCNDBP1 (CCNDBP1 Products )
Synonyms
CCNDBP1 antibody, dip1 antibody, gcip antibody, DIP1 antibody, GCIP antibody, HHM antibody, AU022347 antibody, Maid antibody, SECC-8 antibody, SSEC-8 antibody, cyclin D1 binding protein 1 antibody, cyclin D-type binding-protein 1 antibody, CCNDBP1 antibody, ccndbp1 antibody, Ccndbp1 antibody
Background
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.Synonyms: Cyclin-D1-binding protein 1, DIP1, GCIP, Grap2 and cyclin-D-interacting protein, HHM, Human homolog of Maid, MAID
Molecular Weight
40.3 kDa (NP_036274.3)
Gene ID
23582
NCBI Accession
NP_036274
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