BHLHE22 antibody (N-Term)

Catalog No. ABIN1105525

Product Details anti-BHLHE22 Antibody

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHE22 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPAGAALCLK YGESASRGSV AESSGGEQSP DDDSDGRCEL VLRAGVADPR

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-BHLHB5 antibody: synthetic peptide directed towards the N terminal of human BHLHB5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Alternative Name: BHLHB5 / BHLHE22 (BHLHE22 Products)

Synonyms: bhlhb5 antibody, MGC145865 antibody, BHLHE22 antibody, Beta3.1 antibody, wu:fq25e11 antibody, zgc:64225 antibody, BHLHB5 antibody, Beta3 antibody, CAGL85 antibody, TNRC20 antibody, Bhlhb5 antibody, basic helix-loop-helix family member e22 antibody, basic helix-loop-helix family, member e22 antibody, bhlhe22 antibody, BHLHE22 antibody, Bhlhe22 antibody

Background: BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration. BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.Synonyms: Class B basic helix-loop-helix protein 5, Class E basic helix-loop-helix protein 22, TNRC20, Trinucleotide repeat-containing gene 20 protein

Gene ID: 27319

NCBI Accession: NP_689627