Asialoglycoprotein Receptor 2 antibody (N-Term)

Catalog No. ABIN1105450

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Binding Specificity: N-Term

Reactivity: Human, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: LVVICVTGSQ SEGHRGAQLQ AELRSLKEAF SNFSSSTLTE VQAISTHGGS

Cross-Reactivity (Details): Species reactivity (expected):DrosophilaSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-ASGR2 antibody: synthetic peptide directed towards the N terminal of human ASGR2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -28 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -28 °C long term.

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2 (ASGR2 Products)

Synonyms: ASGR2 antibody, asgr2 antibody, MGC137129 antibody, ASGP-R2 antibody, ASGPR2 antibody, CLEC4H2 antibody, HBXBP antibody, HL-2 antibody, Asgr antibody, Asgr-2 antibody, asialoglycoprotein receptor 2 antibody, C-type lectin domain family 10 member A antibody, ASGR2 antibody, clec10a antibody, Asgr2 antibody, LOC100347178 antibody

Background: ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.Synonyms: ASGP-R 2, ASGPR 2, Asialoglycoprotein receptor 2, Hepatic lectin H2

Gene ID: 433

NCBI Accession: NP_001172

Pathways: Thyroid Hormone Synthesis