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SDF1 beta antibody
SDF1b
Reactivity: Rat
WB, IP, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SDF1 beta Antibody
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Target
See all SDF1 beta (SDF1b) Antibodies
SDF1 beta (SDF1b)
(Stromal Cell Derived Factor 1 beta (SDF1b))
Reactivity
Rat
Host
All hosts for SDF1 beta antibodies
Rabbit
Clonality
All clonalities for SDF1 beta antibodies
Polyclonal
Conjugate
All conjugates for SDF1 beta antibodies
This SDF1 beta antibody is un-conjugated
Application
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Specificity
Cross-reactivity to SDF-1b of other species has not been determined
Immunogen
This polyclonal antibody, which reacts with both mouse and rat SDF-1b, was generated using E. coli-expressed mouse SDF-1b as an immunogen.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
The tested titer for Western blot is 1:1,000, immunoprecipitation, 1:300-500; and immunohistochemistry, 1:100-500.
Restrictions
For Research Use only
Handling
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Format
Lyophilized
Concentration
1mg/ml
Storage
4 °C
Target Details for SDF1 beta
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Target
SDF1 beta (SDF1b)
(Stromal Cell Derived Factor 1 beta (SDF1b))
Alternative Name
SDF-1 beta (Stromal Cell-Derived Factor, PBSF) (SDF1b Products )
Synonyms
Pbsf antibody, Scyb12 antibody, Sdf1 antibody, Tlsf antibody, Tpar1 antibody, sdf1a antibody, SDF-1 antibody, chemokine (C-X-C motif) ligand 12 antibody, C-X-C motif chemokine ligand 12 antibody, Cxcl12 antibody, cxcl12 antibody, CXCL12 antibody
Background
SDF-1ß (stromal cell-derived factor-ß )1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.
UniProt
P48061
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