MEF2C antibody (AA 1-125)

Catalog No. ABIN1098145

Product Details anti-MEF2C Antibody

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Binding Specificity: AA 1-125

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purpose: MEF2C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MEF2C (AA: 1-125) expressed in E. Coli.

Clone: 6H2G2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MEF2C antibody (ABIN1098145)

Xu, Cao, Wang, Xu, Chen, Xu: "VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C." in: PLoS ONE, Vol. 6, Issue 11, pp. e27165, (2011) (PubMed).

Stephens, Stephens, Hobbs, Hutmacher, Bacic-Welsh, Woodruff, Morrison: "Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization." in: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 30071-86, (2011) (PubMed).

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C (MEF2C Products)

Background:

Description: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Aliases: DEL5q14.3, C5DELq14.3

Molecular Weight: 51.2kDa

Gene ID: 4208

HGNC: 4208

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling