BPIFA2 antibody (AA 16-250)

Catalog No. ABIN1098132

Product Details anti-BPIFA2 Antibody

Target: BPIFA2 (BPI Fold Containing Family A, Member 2 (BPIFA2))

Binding Specificity: AA 16-250

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BPIFA2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: human Splunc2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Splunc2 (AA: 16-250) expressed in E. Coli.

Clone: 4C7D7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-BPIFA2 antibody (ABIN1098132)

Bingle, Barnes, Lunn, Musa, Webster, Douglas, Cross, High, Bingle: "Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein." in: Histochemistry and cell biology, Vol. 132, Issue 3, pp. 339-49, (2009) (PubMed).

Vargas, Speight, Bingle, Barrett, Bingle: "Expression of PLUNC family members in benign and malignant salivary gland tumours." in: Oral diseases, Vol. 14, Issue 7, pp. 613-9, (2008) (PubMed).

Target Details for BPIFA2

Target: BPIFA2 (BPI Fold Containing Family A, Member 2 (BPIFA2))

Alternative Name: Splunc2 (BPIFA2 Products)

Synonyms: C20orf70 antibody, PSP antibody, SPLUNC2 antibody, bA49G10.1 antibody, Bpifa2e antibody, Psp antibody, BPI fold containing family A member 2 antibody, BPI fold containing family A, member 2 antibody, BPIFA2 antibody, Bpifa2 antibody

Background:

Description: SPLUNC2 is one member of PLUNC family, the gene undergoes alternative splicing using two 5' non-coding exons, suggesting that the gene is regulated by alternative promoters.multiple SPLUNC2 isoforms are found in the oral cavity and suggest that these proteins may be differentially regulated in distinct tissues where they may function in the innate immune response. Mucin plugs, mucous and intermediate cells of mucoepidermoid carcinomas were positive for LPLUNC1 and SPLUNC2, but areas composed of epidermoid and clear cells were negative for all PLUNCs. Papillary cystadenocarcinoma was positive for all PLUNCs.

Aliases: BPIFA2, PSP, SPLUNC2, C20orf70, bA49G10.1

Molecular Weight: 27kDa

Gene ID: 140683

HGNC: 140683

UniProt: Q96DR5