TRIP6 antibody (AA 107-291)

Catalog No. ABIN1098130

Product Details anti-TRIP6 Antibody

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Binding Specificity: AA 107-291

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: TRIP6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TRIP6 (AA: 107-291) expressed in E. Coli.

Clone: 6H4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-TRIP6 antibody (ABIN1098130)

Willier, Butt, Richter, Burdach, Grunewald: "Defining the role of TRIP6 in cell physiology and cancer." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 103, Issue 12, pp. 573-91, (2011) (PubMed).

Lai, Lin, Zheng, Benveniste, Lin: "The adaptor protein TRIP6 antagonizes Fas-induced apoptosis but promotes its effect on cell migration." in: Molecular and cellular biology, Vol. 30, Issue 23, pp. 5582-96, (2010) (PubMed).

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6 (TRIP6 Products)

Synonyms: TRIP6 antibody, OIP-1 antibody, OIP1 antibody, TRIP-6 antibody, TRIP6i2 antibody, ZRP-1 antibody, thyroid hormone receptor interactor 6 antibody, TRIP6 antibody, Trip6 antibody

Background:

Description: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.

Aliases: OIP1, OIP-1, ZRP-1, TRIP-6, TRIP6i2

Molecular Weight: 50.3kDa

Gene ID: 7205

HGNC: 7205

UniProt: Q15654

Pathways: Cell-Cell Junction Organization