RAG1 antibody (AA 818-868)

Catalog No. ABIN1098121

Product Details anti-RAG1 Antibody

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Binding Specificity: AA 818-868

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAG1 antibody is un-conjugated

Application: ELISA

Purpose: RAG1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.

Clone: 1D9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RAG1 antibody (ABIN1098121)

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Target Details for RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Alternative Name: RAG1 (RAG1 Products)

Synonyms: RAG-1 antibody, rag1 antibody, RNF74 antibody, Rag-1 antibody, rag-1 antibody, rag1a antibody, recombination activating 1 antibody, recombination activating gene 1 antibody, recombination activating gene 1 S homeolog antibody, Rag1 antibody, RAG1 antibody, rag1 antibody, rag1.S antibody

Background:

Description: The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.

Aliases: RAG-1, RNF74, MGC43321

Molecular Weight: 119kDa

Gene ID: 5896

HGNC: 5896

UniProt: P15918