CD166 antibody (AA 405-524)

Catalog No. ABIN1098107

Product Details anti-CD166 Antibody

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Binding Specificity: AA 405-524

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD166 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purpose: AlCAM Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human AlCAM (AA: 405-524) expressed in E. Coli.

Clone: 5B3

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD166 antibody (ABIN1098107)

Rauch, Rosenkranz, Böhm, Meyer-Kirchrath, Hohlfeld, Schrör, Rauch: "Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes." in: Vascular pharmacology, Vol. 54, Issue 3-6, pp. 93-9, (2011) (PubMed).

Liang, Huang, Jia, Wang: "Activated leukocyte cell adhesion molecule expression is up-regulated in the development of endometrioid carcinoma." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 21, Issue 3, pp. 523-8, (2011) (PubMed).

Target Details for CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Alternative Name: AlCAM (ALCAM Products)

Synonyms: CD166 antibody, MEMD antibody, ALCAM antibody, BEN antibody, DM-GRASP antibody, JC7 antibody, SC1 antibody, AI853494 antibody, MuSC antibody, alcam antibody, cd166 antibody, memd antibody, fb53h09 antibody, fb80a10 antibody, nlcam antibody, si:ch211-190h2.4 antibody, wu:fb53h09 antibody, wu:fb80a10 antibody, wu:fc14b01 antibody, activated leukocyte cell adhesion molecule antibody, activated leukocyte cell adhesion molecule a antibody, activated leukocyte cell adhesion molecule L homeolog antibody, CD166 antigen homolog antibody, activated leukocyte cell adhesion molecule b antibody, ALCAM antibody, Alcam antibody, alcama antibody, alcam.L antibody, alcam antibody, cd166 antibody, alcamb antibody

Background:

Description: This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Aliases: MEMD, CD166, FLJ38514, MGC71733

Molecular Weight: 65.1kDa

Gene ID: 214

HGNC: 214

UniProt: Q13740