GZMK antibody

Catalog No. ABIN108720

Product Details anti-GZMK Antibody

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMK antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)

Specificity: The antibodies do not cross-react with the human granzymes A, B or M.

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human Granzyme K

Clone: GM-24C3

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: Granzyme K (GZMK Products)

Synonyms: TRYP2 antibody, granzyme K antibody, GZMK antibody, Gzmk antibody

Background: Granzymes are exogenous serine proteases that are stored in the cytotoxic granules of activated T cells and NK cells. GM24C3 was generated by genetic immunisation and reacts with human granzyme K (GrK), a 28 kDa serine protease with trypsin-like specificity.

UniProt: P49863