IL13RA2 antibody (Extracellular Domain)

Catalog No. ABIN108717

Product Details anti-IL13RA2 Antibody

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL13RA2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)

Specificity: GM1C8 recognises IL-13Ralpha1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (Myrtek et al., 2004).

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human IL13-Ralpha1 (extracellular domain)

Clone: GM-1C8

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for IL13RA2

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Alternative Name: IL13R (IL13RA2 Products)

Synonyms: il-13ra2 antibody, sb:cb602 antibody, si:dkeyp-110c7.6 antibody, CD213A2 antibody, CT19 antibody, IL-13R antibody, IL13BP antibody, CD213a2 antibody, IL-13R-alpha-2 antibody, IL13RA2 antibody, interleukin 13 receptor, alpha 2 antibody, interleukin 13 receptor subunit alpha 2 antibody, interleukin 13 receptor subunit alpha 2 S homeolog antibody, il13ra2 antibody, IL13RA2 antibody, il13ra2.S antibody, Il13ra2 antibody

Background: Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.

UniProt: P78552