HNRNPA2B1 antibody

Catalog No. ABIN108621

Product Details anti-HNRNPA2B1 Antibody

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Reactivity: Human, Mouse, Rat, Pig, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNRNPA2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts predominantly with a 36 kDa band (A2), a 38 kDa band (B1)

Purification: Protein A

Immunogen: Full length bacterially expressed His-hnRNP-A2 fusion protein (Human)

Clone: DP3B3

Isotype: IgG2a

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try,IHC-Fr: 1/100. PubMed: 17067748Fix with acetoneWB: 1/1500 - 1/6000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa)IHC-P: Use a concentration of 1 μg/mL

Comment:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-HNRNPA2B1 antibody (ABIN108621)

Rambaruth, Greenwell, Dwek: "The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer." in: Glycobiology, Vol. 22, Issue 6, pp. 839-48, (2012) (PubMed).

Maeto, Knott, Linero, Ellenberg, Scolaro, Castilla: "Differential effect of acute and persistent Junin virus infections on the nucleo-cytoplasmic trafficking and expression of heterogeneous nuclear ribonucleoproteins type A and B." in: The Journal of general virology, Vol. 92, Issue Pt 9, pp. 2181-90, (2011) (PubMed).

Santarosa, Del Col, Viel, Bivi, DAmbrosio, Scaloni, Tell, Maestro: "BRCA1 modulates the expression of hnRNPA2B1 and KHSRP." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 23, pp. 4666-73, (2011) (PubMed).

Clower, Chatterjee, Wang, Cantley, Vander Heiden, Krainer: "The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 1894-9, (2010) (PubMed).

Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, (2010) (PubMed).

Lee, Horak, Khanna, Meng, Yu, Veenstra, Steeg: "Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility." in: Cancer research, Vol. 68, Issue 3, pp. 639-44, (2008) (PubMed).

Zech, Dlaska, Tzankov, Hilbe: "Prognostic and diagnostic relevance of hnRNP A2/B1, hnRNP B1 and S100 A2 in non-small cell lung cancer." in: Cancer detection and prevention, Vol. 30, Issue 5, pp. 395-402, (2006) (PubMed).

Strom, Diecke, Hunsmann, Stuke: "Identification of prion protein binding proteins by combined use of far-Western immunoblotting, two dimensional gel electrophoresis and mass spectrometry." in: Proteomics, Vol. 6, Issue 1, pp. 26-34, (2006) (PubMed).

Hong, Suh, Kwon, Ko, Choi, Moon, Yoo, Son, Park, Lee, Yoon: "Proteomic analysis of differential protein expression in response to epidermal growth factor in neonatal porcine pancreatic cell monolayers." in: Journal of cellular biochemistry, Vol. 95, Issue 4, pp. 769-81, (2005) (PubMed).

Xia: "Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 13171-8, (2005) (PubMed).

Kamma, Horiguchi, Wan, Matsui, Fujiwara, Fujimoto, Yazawa, Dreyfuss: "Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms." in: Experimental cell research, Vol. 246, Issue 2, pp. 399-411, (1999) (PubMed).

Target Details for HNRNPA2B1

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Alternative Name: hnRNP A2B1  (HNRNPA2B1 Products)

Background: Synonyms:
Heterogeneous nuclear ribonucleoprotein A2 antibody,Heterogeneous nuclear ribonucleoprotein A2/B1antibody,Heterogeneous nuclear ribonucleoprotein B1 antibody,Heterogeneous nuclear ribonucleoproteins A2/B1antibody,hnRNP A2 antibody,hnRNP A2 / hnRNP B1 antibody,hnRNP B1 antibody,hnRNP-A2 antibody,hnRNP-B1antibody,hnRNPA2 antibody,hnRNPB1 antibody,HNRPA2 antibody,HNRPA2B1 antibody,HNRPB1 antibody,Nuclearribonucleoprotein particle A2 protein antibody,RNP A2 antibody,RNP B1 antibody,RNP-A2 antibody,RNP-B1antibody,RNPA2 antibody,RNPB1 antibody,SNRPB1 antibody

Gene ID: 3181, 117282

OMIM: 600124

UniProt: O88569, P22626