HNRNPA2B1 antibody

Catalog No. ABIN108621

Product Details anti-HNRNPA2B1 Antibody

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Reactivity: Human, Mouse, Rat, Pig, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNRNPA2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts predominantly with a 36 kDa band (A2), a 38 kDa band (B1)

Purification: Protein A

Immunogen: Full length bacterially expressed His-hnRNP-A2 fusion protein (Human)

Clone: DP3B3

Isotype: IgG2a

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try,IHC-Fr: 1/100. PubMed: 17067748Fix with acetoneWB: 1/1500 - 1/6000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa)IHC-P: Use a concentration of 1 μg/mL

Comment:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-HNRNPA2B1 antibody (ABIN108621)

Rambaruth, Greenwell, Dwek: "The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer." in: Glycobiology, Vol. 22, Issue 6, pp. 839-48, (2012) (PubMed).

Maeto, Knott, Linero, Ellenberg, Scolaro, Castilla: "Differential effect of acute and persistent Junin virus infections on the nucleo-cytoplasmic trafficking and expression of heterogeneous nuclear ribonucleoproteins type A and B." in: The Journal of general virology, Vol. 92, Issue Pt 9, pp. 2181-90, (2011) (PubMed).

Santarosa, Del Col, Viel, Bivi, DAmbrosio, Scaloni, Tell, Maestro: "BRCA1 modulates the expression of hnRNPA2B1 and KHSRP." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 23, pp. 4666-73, (2011) (PubMed).

Clower, Chatterjee, Wang, Cantley, Vander Heiden, Krainer: "The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 1894-9, (2010) (PubMed).

Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, (2010) (PubMed).

Lee, Horak, Khanna, Meng, Yu, Veenstra, Steeg: "Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility." in: Cancer research, Vol. 68, Issue 3, pp. 639-44, (2008) (PubMed).

Zech, Dlaska, Tzankov, Hilbe: "Prognostic and diagnostic relevance of hnRNP A2/B1, hnRNP B1 and S100 A2 in non-small cell lung cancer." in: Cancer detection and prevention, Vol. 30, Issue 5, pp. 395-402, (2006) (PubMed).

Strom, Diecke, Hunsmann, Stuke: "Identification of prion protein binding proteins by combined use of far-Western immunoblotting, two dimensional gel electrophoresis and mass spectrometry." in: Proteomics, Vol. 6, Issue 1, pp. 26-34, (2006) (PubMed).

Hong, Suh, Kwon, Ko, Choi, Moon, Yoo, Son, Park, Lee, Yoon: "Proteomic analysis of differential protein expression in response to epidermal growth factor in neonatal porcine pancreatic cell monolayers." in: Journal of cellular biochemistry, Vol. 95, Issue 4, pp. 769-81, (2005) (PubMed).

Xia: "Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 13171-8, (2005) (PubMed).

Kamma, Horiguchi, Wan, Matsui, Fujiwara, Fujimoto, Yazawa, Dreyfuss: "Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms." in: Experimental cell research, Vol. 246, Issue 2, pp. 399-411, (1999) (PubMed).

Target Details for HNRNPA2B1

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Alternative Name: hnRNP A2B1  (HNRNPA2B1 Products)

Synonyms: HNRNPA2 antibody, HNRNPB1 antibody, HNRPA2 antibody, HNRPA2B1 antibody, HNRPB1 antibody, RNPA2 antibody, SNRPB1 antibody, hnrpa2b1 antibody, MGC53135 antibody, HNRNPA2B1 antibody, hnrnpa2 antibody, hnrnpb1 antibody, hnrpa2 antibody, hnrpb1 antibody, rnpa2 antibody, snrpb1 antibody, 9130414A06Rik antibody, Hnrpa2 antibody, Hnrpa2b1 antibody, hnrnp-A antibody, hnRNP antibody, heterogeneous nuclear ribonucleoprotein A2/B1 antibody, heterogeneous nuclear ribonucleoprotein A2/B1 S homeolog antibody, heterogeneous nuclear ribonucleoproteins A2/B1 antibody, HNRNPA2B1 antibody, hnrnpa2b1.S antibody, hnrnpa2b1 antibody, Hnrnpa2b1 antibody, LOC100353281 antibody

Background: Synonyms:
Heterogeneous nuclear ribonucleoprotein A2 antibody,Heterogeneous nuclear ribonucleoprotein A2/B1antibody,Heterogeneous nuclear ribonucleoprotein B1 antibody,Heterogeneous nuclear ribonucleoproteins A2/B1antibody,hnRNP A2 antibody,hnRNP A2 / hnRNP B1 antibody,hnRNP B1 antibody,hnRNP-A2 antibody,hnRNP-B1antibody,hnRNPA2 antibody,hnRNPB1 antibody,HNRPA2 antibody,HNRPA2B1 antibody,HNRPB1 antibody,Nuclearribonucleoprotein particle A2 protein antibody,RNP A2 antibody,RNP B1 antibody,RNP-A2 antibody,RNP-B1antibody,RNPA2 antibody,RNPB1 antibody,SNRPB1 antibody

Gene ID: 3181, 117282

OMIM: 600124

UniProt: O88569, P22626