FMR1 antibody (C-Term)

Catalog No. ABIN108598

Product Details anti-FMR1 Antibody

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Binding Specificity: C-Term

Reactivity: Drosophila melanogaster

Host: Mouse

Clonality: Monoclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

No Cross-Reactivity: Human

Cross-Reactivity (Details): Fruit fly (Drosophila melanogaster) Does not react with Human

Purification: Protein A

Immunogen: His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa).

Clone: 6A15

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try at IP: Use at 25 μg/mg of lysate WB: Use at an assay dependent dilution. Detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa)

Comment:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-FMR1 antibody (ABIN108598)

Callan, Clements, Ahrendt, Zarnescu: "Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain." in: Brain research, Vol. 1462, pp. 151-61, (2012) (PubMed).

Lim, Lee, Choi, Kilman, Kim, Park, Jang, Allada, Choe: "The novel gene twenty-four defines a critical translational step in the Drosophila clock." in: Nature, Vol. 470, Issue 7334, pp. 399-403, (2011) (PubMed).

Monzo, Dowd, Minden, Sisson: "Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila." in: Developmental biology, Vol. 340, Issue 2, pp. 408-18, (2010) (PubMed).

Callan, Cabernard, Heck, Luois, Doe, Zarnescu: "Fragile X protein controls neural stem cell proliferation in the Drosophila brain." in: Human molecular genetics, Vol. 19, Issue 15, pp. 3068-79, (2010) (PubMed).

Kwak, Drier, Barbee, Ramaswami, Yin, Wickens: "GLD2 poly(A) polymerase is required for long-term memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 38, pp. 14644-9, (2008) (PubMed).

Monzo, Papoulas, Cantin, Wang, Yates, Sisson: "Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 48, pp. 18160-5, (2006) (PubMed).

Wan, Dockendorff, Jongens, Dreyfuss: "Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein." in: Molecular and cellular biology, Vol. 20, Issue 22, pp. 8536-47, (2000) (PubMed).

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: Drosophila FMR1 (FMR1 Products)

Synonyms: AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody

Background: Synonyms:
Drosophila FMR1 antibody,dFMR antibody,dFMR1 antibody,dFXR antibody,Drosophila fragile X mentalretardation protein antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation1 protein antibody,fragile X mental retardation protein antibody,FRAXA antibody,Protein FMR1antibody

Gene ID: 37528, 23879

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development