BCL3 antibody (C-Term)
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- Target See all BCL3 Antibodies
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BCL3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.
- Isotype
- IgG
- Top Product
- Discover our top product BCL3 Primary Antibody
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- Application Notes
- BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.
- Comment
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(CT) B-cell CLL/lymphoma 3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
- Storage Comment
- BCL3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- Alternative Name
- BCL3 (BCL3 Products)
- Synonyms
- BCL3 antibody, AI528691 antibody, Bcl-3 antibody, BCL4 antibody, D19S37 antibody, B-cell CLL/lymphoma 3 antibody, B cell leukemia/lymphoma 3 antibody, BCL3 antibody, Bcl3 antibody
- Background
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The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-k-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-k-B proteins. The expression of this gene can be induced by NF-k-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-k-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Synonyms: B-cell CLL/lymphoma 3, BCL-3, BCL4, D19S37, Proto-oncogene BCL3 - Molecular Weight
- 50 kDa (calculated)
- Gene ID
- 602
- NCBI Accession
- NP_005169
- Pathways
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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