BATF antibody (N-Term)
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- Target See all BATF Antibodies
- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BATF antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- Specificity
- Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF.
- Isotype
- IgG
- Top Product
- Discover our top product BATF Primary Antibody
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- Application Notes
- BATF antibody can be used for detection of BATF by Western blot at 0.5 μg/mL. For immunofluorescence start at 20 μg/mL.
- Comment
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(NT) B-cell activating transcription factor
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
- Storage Comment
- BATF antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
- Alternative Name
- BATF (BATF Products)
- Synonyms
- B-ATF antibody, si:ch211-153j24.4 antibody, BATF1 antibody, SFA-2 antibody, SFA2 antibody, basic leucine zipper transcription factor, ATF-like antibody, basic leucine zipper ATF-like transcription factor antibody, batf antibody, BATF antibody, Batf antibody
- Background
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BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Synonyms: B-cell activating transcription factor, BATF1, basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2 - Molecular Weight
- 14 kDa
- Gene ID
- 10538
- NCBI Accession
- NP_006390
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