CMPK2 antibody (C-Term)
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- Target See all CMPK2 Antibodies
- CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CMPK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificity
- Multiple isoforms of CMPK2 are known to exist.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.
- Isotype
- IgG
- Top Product
- Discover our top product CMPK2 Primary Antibody
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- Application Notes
- CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
- Comment
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(CT) Cytidine monophosphate (UMP-CMP) kinase 2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C
- Storage Comment
- CMPK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))
- Alternative Name
- CMPK2 (CMPK2 Products)
- Synonyms
- si:ch211-276e8.3 antibody, TMPK2 antibody, TYKi antibody, UMP-CMPK2 antibody, 1200004E04Rik antibody, TDKI antibody, Tyki antibody, cytidine/uridine monophosphate kinase 2 antibody, cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial antibody, CMPK2 antibody, cmpk2 antibody, Cmpk2 antibody
- Background
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UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Synonyms: Cytidine monophosphate (UMP-CMP) kinase 2, TMPK2, TYKi, UMP-CMPK2 - Molecular Weight
- 49 kDa
- Gene ID
- 129607
- NCBI Accession
- NP_997198
- Pathways
- Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin
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