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Gelsolin antibody (N-Term)

Verified GSN Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN1019662
  • Target See all Gelsolin (GSN) Antibodies
    Gelsolin (GSN)
    Binding Specificity
    • 16
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 96
    • 36
    • 30
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 79
    • 26
    • 1
    Goat
    Clonality
    • 73
    • 33
    Polyclonal
    Conjugate
    • 57
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gelsolin antibody is un-conjugated
    Application
    • 75
    • 29
    • 22
    • 20
    • 18
    • 16
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Gelsolin (isoform a)
    Sequence
    PQGRVPEARP NS
    Specificity
    This antibody is expected to recognize isoform a (NP_000168.1) only . Reported variants represent identical protein: NP_001121138.1, NP_001121139.1 Reported variants represent identical protein: NP_001121135.1, NP_937895.1, NP_001121134.1, NP_001121137.1,
    Cross-Reactivity
    Human
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence PQGRVPEARPNS-C, from the N Terminus of the protein sequence according to NP_000168.1, NP_937895.1, NP_001121138.1.
    Isotype
    IgG
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    Discover our top product GSN Primary Antibody
  • Application Notes

    Western Blot: Approx 100 kDa band observed in Human Colon, Duodenum, Heart and Skeletal Muscle lysates (calculated MW of 85.7 kDa according to NP_000168.1). Recommended concentration: 1-3 μg/mL. Primary incubation 1 hour at room temperature.

    Peptide ELISA: antibody detection limit dilution 1:64000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    Gelsolin (GSN)
    Alternative Name
    GSN (GSN Products)
    Background
    GSN, gelsolin, ADF, AGEL, DKFZp313L0718, OTTHUMP00000022011, OTTHUMP00000022014, OTTHUMP00000162202, actin-depolymerizing factor, brevin
    Gene ID
    2934
    NCBI Accession
    NP_000168, NP_937895, NP_001121138
    Pathways
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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