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NIPBL antibody (AA 344-356)

NIPBL Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN100654
  • Target See all NIPBL Antibodies
    NIPBL (Nipped-B like Protein (NIPBL))
    Binding Specificity
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 344-356
    Reactivity
    • 16
    • 14
    • 5
    Human
    Host
    • 25
    • 3
    • 1
    • 1
    Goat
    Clonality
    • 26
    • 4
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NIPBL antibody is un-conjugated
    Application
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    ELISA, Western Blotting (WB)
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Sterility
    Sterile filtered
    Immunogen
    This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 344-356 of Human IDN3.
    Isotype
    IgG
    Top Product
    Discover our top product NIPBL Primary Antibody
  • Application Notes
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect bands at 316 kDa in size corresponding to IDN3 by western blotting in the appropriate cell lysate or extract.  Splice variants for this protein may show molecular weights of 304 kDa and 122 kDa.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.6 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    NIPBL (Nipped-B like Protein (NIPBL))
    Alternative Name
    IDN3 (NIPBL Products)
    Synonyms
    CDLS antibody, CDLS1 antibody, IDN3 antibody, IDN3-B antibody, Scc2 antibody, SCC2W antibody, scc2 antibody, nipbl antibody, scc2-2 antibody, NIPBL antibody, nipbla antibody, wu:fi33d08 antibody, 4921518A06Rik antibody, 4933421G18Rik antibody, C79399 antibody, Idn3 antibody, NIPBL, cohesin loading factor antibody, Nipped-B homolog-like antibody, NIPBL, cohesin loading factor S homeolog antibody, nipped-B homolog b (Drosophila) antibody, nipped-B-like protein A antibody, Nipped-B homolog (Drosophila) antibody, NIPBL antibody, NIPBLL antibody, nipbl.S antibody, LOC427439 antibody, nipblb antibody, LOC100164947 antibody, nipbl antibody, Nipbl antibody
    Background
    IDN3 (also known as Colon tumor susceptibility 2, DKFZp434L1319, FLJ13648, Mis 4, Scc-2, Delangin and Sister chromatid cohesion protein) is the mammalian homologue of Scc2 in S. cerevisiae and Mis4 in S. pombe. In yeast, this factor was originally identified genetically as being involved in sister chromatid cohesion; subsequent work has determined that it is not involved in cohesion directly but is required for the loading of cohesins onto chromatin during S phase. It shares 37% sequence identity with Nipped-B gene product of Drosophila, which facilitates enhancer-promoter communication of remote enhancers. The Drosophila protein is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair.  IDN3 is a nuclear protein that is widely expressed and found at the highest levels in heart, skeletal muscle, fetal and adult liver, and fetal and adult kidney. The protein is also found, albeit at lower levels of expression in thymus, placenta, peripheral leukocyte and small intestine.  Multiple isoforms of the protein have been reported.
    Synonyms: CDLS antibody, Colon tumor susceptibility 2 antibody, Delangin antibody, DKFZp434L1319 antibody, FLJ11203 antibody
    Gene ID
    25836, 4760549
    UniProt
    Q6KC79
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance
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