Annexin VII Products
(Annexin A7 (ANXA7))
Categories
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008].
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Featured Annexin VII Categories
Annexin VII Antibodies
High quality antibodies with extensive validation data.
Annexin VII ELISA Kits
Reliable ELISA kits for a wide range of species.
Annexin VII Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Annexin VII Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN513369
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3029978
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7144294
Quantity
100 μL
Datasheet
Datasheet
Recommended Annexin VII ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953788
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN509722
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN511905
Quantity
96 tests
Datasheet
Datasheet
Recommended Annexin VII Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345200
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121849
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1096023
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Annexin VII products
: "In vivo and in vitro effect of hepatocarcinoma lymph node metastasis by upregulation of Annexin A7 and relevant mechanisms." in: Tumour biology, (2015) (PubMed).: "Evaluation of Annexin A7, Galectin-3 and Gelsolin as possible biomarkers of hepatocarcinoma lymphatic metastasis." in: Biomedicine & pharmacotherapy, Vol. 68, Issue 3, pp. 259-65, (2014) (PubMed).
: "Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E⁻/⁻mice." in: Cell death & disease, Vol. 4, pp. e806, (2013) (PubMed).
: "Increased expression of annexin A7 in temporal lobe tissue of patients with refractory epilepsy." in: Histology and histopathology, Vol. 26, Issue 5, pp. 571-9, (2011) (PubMed).
: "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." in: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).
: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." in: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).
: "ANX7, a candidate tumor suppressor gene for prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4575-80, (2001) (PubMed).
: "Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33504-9, (1999) (PubMed).
: "Expression and localization of annexin VII (synexin) in muscle cells." in: Journal of cell science, Vol. 108 ( Pt 1), pp. 85-95, (1995) (PubMed).
: "Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 3228-32, (1991) (PubMed).
Synonyms and alternative names related to Annexin VII
annexin A7 (ANXA7), annexin A7 (Anxa7), annexin VII (anxa7), annexin A7 (anxa7), annexin A7 S homeolog (anxa7.S), annexin A7 (PTRG_02166), annexin A7 (BRAFLDRAFT_231082), annexin A7 (PAAG_00136), annexin A7 (MCYG_04180), annexin A7 (VDBG_06328), annexin A7 (MGYG_02426), AI265384, AI316497, ANX7, Anx7, anxa7, ANXA7, MGC76267, MGC82023, MGC83033, SNX, SYNEXIN, synexinProtein level used designations for Annexin VII
- annexin VII
- annexin-7
- annexin A7
- synexin
- annexin A7-like
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