ANKH Products
(Ankylosis, Progressive Homolog (Mouse) (ANKH))
Categories
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008].
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Featured ANKH Categories
ANKH Antibodies
High quality antibodies with extensive validation data.
ANKH Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ANKH Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN653697
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, FACS, IHC (p)
Validations
- (2)
Cat. No.
ABIN1892978
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7264924
Quantity
200 μL
Datasheet
Datasheet
Recommended ANKH Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345071
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3107094
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3130021
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ANKH products
: "Familial calcium pyrophosphate dihydrate deposition disease and the ANKH gene." in: Current opinion in rheumatology, Vol. 15, Issue 3, pp. 326-31, (2003) (PubMed).: "The program of androgen-responsive genes in neoplastic prostate epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11890-5, (2002) (PubMed).
: "Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH." in: American journal of human genetics, Vol. 71, Issue 4, pp. 985-91, (2002) (PubMed).
: "Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK." in: American journal of human genetics, Vol. 68, Issue 6, pp. 1321-6, (2001) (PubMed).
: "Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia." in: Nature genetics, Vol. 28, Issue 1, pp. 37-41, (2001) (PubMed).
: "Role of the mouse ank gene in control of tissue calcification and arthritis." in: Science (New York, N.Y.), Vol. 289, Issue 5477, pp. 265-70, (2000) (PubMed).
Synonyms and alternative names related to ANKH
ANKH inorganic pyrophosphate transport regulator (ANKH), ANKH inorganic pyrophosphate transport regulator (Ankh), progressive ankylosis (Ank), ANKH inorganic pyrophosphate transport regulator b (ankhb), ANKH inorganic pyrophosphate transport regulator S homeolog (ankh.S), ANKH inorganic pyrophosphate transport regulator a (ankha), ANK, Ank, ank, Ankh, ankh, CCAL2, CMDJ, CPPDD, D15Ertd221e, HANK, MANK, mKIAA1581, wu:fc08d03, wu:fj64g09, zgc:110290Protein level used designations for ANKH
- ankylosis, progressive homolog
- progressive ankylosis protein homolog
- progressive ankylosis homolog
- progressive ankylosis protein
- ankylosis, progressive homolog (mouse)
- progressive ankylosis protein homolog-like
- fn54 protein
- ANK-B
- progressive ankylosis protein homolog B
- progressive ankylosis-like protein
- ankylosis, progressive homolog a
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