ANAPC5 Products
(Anaphase Promoting Complex Subunit 5 (ANAPC5))
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This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008].
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Featured ANAPC5 Categories
ANAPC5 Antibodies
High quality antibodies with extensive validation data.
ANAPC5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ANAPC5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (8)
Cat. No.
ABIN950136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
Cat. No.
ABIN6136867
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7144073
Quantity
100 μL
Datasheet
Datasheet
Recommended ANAPC5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345038
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (5)
- (1)
Cat. No.
ABIN1046520
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3089043
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ANAPC5 products
: "Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a." in: PLoS pathogens, Vol. 8, Issue 7, pp. e1002789, (2012) (PubMed).: "Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated ..." in: Journal of virology, Vol. 84, Issue 20, pp. 10832-43, (2010) (PubMed).
: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, (2008) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).
: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).
Synonyms and alternative names related to ANAPC5
anaphase promoting complex subunit 5 (ANAPC5), anaphase promoting complex subunit 5 (anapc5), anaphase-promoting complex subunit 5 (LOC100093215), anaphase promoting complex subunit 5 L homeolog (anapc5.L), anaphase-promoting complex subunit 5 (Anapc5), anaphase-promoting complex subunit (AT1G06590), anaphase-promoting complex subunit Apc5 (apc5), anaphase promoting complex subunit 5 (Anapc5), 2510006G12Rik, AA408751, AA536819, AA986414, ANAPC5, Anpc5, APC5, DDBDRAFT_0206386, DDBDRAFT_0234269, DDB_0206386, DDB_0234269, F12K11.7, F12K11_7, MGC89697, wu:fb75a09, zgc:55800Protein level used designations for ANAPC5
- anaphase-promoting complex subunit 5
- cyclosome subunit 5
- APC5
- anaphase promoting complex subunit 5
- anaphase-promoting complex subunit 5-like
- 20S cyclosome/APC complex protein apc5
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