Amphiregulin Products
(Amphiregulin (AREG))
Categories
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq, Jul 2008].
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Featured Amphiregulin Categories
Amphiregulin Antibodies
High quality antibodies with extensive validation data.
Amphiregulin ELISA Kits
Reliable ELISA kits for a wide range of species.
Amphiregulin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Amphiregulin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7428263
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (5)
Cat. No.
ABIN704996
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6137065
Quantity
100 μL
Datasheet
Datasheet
Recommended Amphiregulin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (5)
Cat. No.
ABIN6720551
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6953670
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6961965
Quantity
96 tests
Datasheet
Datasheet
Recommended Amphiregulin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
Cat. No.
ABIN5509497
Quantity
15 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273804
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7273805
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Amphiregulin products
: "Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG." in: International journal of molecular medicine, Vol. 45, Issue 4, pp. 1163-1175, (2020) (PubMed).: "Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis." in: Journal of hematology & oncology, Vol. 12, Issue 1, pp. 2, (2019) (PubMed).
: "CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17." in: International journal of biological sciences, Vol. 15, Issue 2, pp. 493-506, (2019) (PubMed).
: "The impact of co-expression of wild-type EGFR and its ligands determined by immunohistochemistry for response to treatment with cetuximab in patients with metastatic colorectal cancer." in: Oncotarget, Vol. 8, Issue 5, pp. 7666-7677, (2018) (PubMed).
: "Amphiregulin Antibody and Reduction of Axial Elongation in Experimental Myopia." in: EBioMedicine, Vol. 17, pp. 134-144, (2017) (PubMed).
: "Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats." in: The Journal of steroid biochemistry and molecular biology, Vol. 174, pp. 234-241, (2017) (PubMed).
: "Amphiregulin confers trastuzumab resistance via AKT and ERK activation in HER2-positive breast cancer." in: Journal of cancer research and clinical oncology, Vol. 142, Issue 1, pp. 157-65, (2016) (PubMed).
: "Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer." in: Oncotarget, Vol. 7, Issue 4, pp. 4925-38, (2016) (PubMed).
: "GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 251-63, (2016) (PubMed).
: "Mast Cells Participate in Corneal Development in Mice." in: Scientific reports, Vol. 5, pp. 17569, (2016) (PubMed).
Synonyms and alternative names related to Amphiregulin
amphiregulin (AREG), amphiregulin (Areg), AR, AREG, AREG/SDGF, AREGB, CRDGF, SDGF, SdgfProtein level used designations for Amphiregulin
- colorectum cell-derived growth factor
- schwannoma-derived growth factor
- AR
- SDGF
- amphiregulin (schwannoma-derived growth factor)
- amphiregulin long form
- amphiregulin
- amphiregulin B
- Schwannoma-derived growth factor
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