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AMFR Products

(Autocrine Motility Factor Receptor (AMFR))
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012].

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Featured AMFR Categories

AMFR Antibodies

High quality antibodies with extensive validation data.

AMFR ELISA Kits

Reliable ELISA kits for a wide range of species.

AMFR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AMFR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7444268
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (1)
  • (4)
Cat. No. ABIN388938
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (7)
Cat. No. ABIN3030083
Quantity 0.4 mL
Datasheet Datasheet

Recommended AMFR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6965094
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131057
Quantity 96 tests
Datasheet Datasheet

Recommended AMFR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344980
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417966
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417981
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AMFR products

Lucarelli, Galleggiante, Rutigliano, Sanguedolce, Cagiano, Bufo, Lastilla, Maiorano, Ribatti, Giglio, Serino, Vavallo, Bettocchi, Selvaggi, Battaglia, Ditonno: "Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma." in: Oncotarget, Vol. 6, Issue 15, pp. 13371-86, (2015) (PubMed).

Lucarelli, Rutigliano, Sanguedolce, Galleggiante, Giglio, Cagiano, Bufo, Maiorano, Ribatti, Ranieri, Gigante, Gesualdo, Ferro, de Cobelli, Buonerba, Di Lorenzo, De Placido, Palazzo, Bettocchi et al.: "Increased Expression of the Autocrine Motility Factor is Associated With Poor Prognosis in Patients With Clear Cell-Renal Cell Carcinoma. ..." in: Medicine, Vol. 94, Issue 46, pp. e2117, (2015) (PubMed).

Lin, Lan, Chau: "TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation." in: Oncogene, Vol. 32, Issue 18, pp. 2325-34, (2013) (PubMed).

Araki, Shimura, Yajima, Tsutsumi, Suzuki, Okada, Kobayashi, Raz, Kuwano: "Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32305-11, (2009) (PubMed).

Fang, Ferrone, Yang, Jensen, Tiwari, Weissman: "The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 25, pp. 14422-7, (2001) (PubMed).

Synonyms and alternative names related to AMFR

autocrine motility factor receptor (AMFR), autocrine motility factor receptor (Amfr), autocrine motility factor receptor L homeolog (amfr.L), autocrine motility factor receptor a (amfra), autocrine motility factor receptor (amfr), autocrine motility factor receptor, amfr (AaeL_AAEL005881), autocrine motility factor receptor (CpipJ_CPIJ016043), putative autocrine motility factor receptor, amfr (Smp_047420), GP78, gp78, RNF45, rnf45, wu:fi06e06, wu:fi37e05, zgc:63893

Protein level used designations for AMFR

  • E3 ubiquitin-protein ligase AMFR
  • RING finger protein 45
  • AMF receptor
  • autocrine motility factor receptor
  • autocrine motility factor receptor, amfr
  • autocrine motility factor receptor amfr
  • autocrine motility factor receptor, isoform 2-like
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