AMACR Products
(alpha-Methylacyl-CoA Racemase (AMACR))
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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].
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Featured AMACR Categories
AMACR Antibodies
High quality antibodies with extensive validation data.
AMACR ELISA Kits
Reliable ELISA kits for a wide range of species.
AMACR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AMACR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (7)
Cat. No.
ABIN6939431
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), FACS
Validations
- (5)
Cat. No.
ABIN654069
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC
Validations
- (2)
- (4)
Cat. No.
ABIN968957
Quantity
100 μL
Datasheet
Datasheet
Recommended AMACR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964773
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953651
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN4993314
Quantity
96 tests
Datasheet
Datasheet
Recommended AMACR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121802
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344965
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409431
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AMACR products
: "mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma." in: Cell reports, Vol. 24, Issue 5, pp. 1093-1104.e6, (2018) (PubMed).: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).
: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).
: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).
: "Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy." in: Nature genetics, Vol. 24, Issue 2, pp. 188-91, (2000) (PubMed).
: "In mouse alpha -methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20887-95, (2000) (PubMed).
Synonyms and alternative names related to AMACR
alpha-methylacyl-CoA racemase (AMACR), alpha-methylacyl-CoA racemase (mcr), PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) (mcr), alpha-methylacyl-CoA racemase (BPSL0064), Alpha-methylacyl-CoA racemase (Maqu_2037), alpha-methylacyl-CoA racemase (UREG_03852), alpha-methylacyl-CoA racemase (MCYG_01809), alpha-methylacyl-CoA racemase (amacr), alpha-methylacyl-CoA racemase L homeolog (amacr.L), alpha-methylacyl-CoA racemase (MGYG_04259), alpha-methylacyl-CoA racemase (NCU04099), alpha-methylacyl-CoA racemase (Amacr), AMACR, amacr, AMACRD, CBAS4, Da1-8, DKFZp469O1232, Macr1, Marc1, MGC89832, NCU04099.1, RACE, RMProtein level used designations for AMACR
- alpha-methylacyl-CoA racemase
- Alpha-methylacyl-CoA racemase
- alpha-methylacyl-CoA racemase-like
- amacr protein
- 2-methylacyl-CoA racemase
- 2-arylpropionyl-CoA epimerase
- alpha-methylacyl-Coenzyme A racemase
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