ALT Products
(Alanine Aminotransferase (ALT))
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This gene encodes cytosolic alanine aminotransaminase 1 (ALT1)\; also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009].
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Featured ALT Categories
ALT Antibodies
High quality antibodies with extensive validation data.
ALT ELISA Kits
Reliable ELISA kits for a wide range of species.
ALT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ALT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (11)
Cat. No.
ABIN7438472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (6)
Cat. No.
ABIN7429409
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7429412
Quantity
100 μL
Datasheet
Datasheet
Recommended ALT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (10)
- (5)
Cat. No.
ABIN6730944
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6730902
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (10)
- (1)
Cat. No.
ABIN6953568
Quantity
96 tests
Datasheet
Datasheet
Recommended ALT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355674
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7194188
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121760
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ALT products
: "Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects." in: Journal of inflammation research, Vol. 14, pp. 6305-6316, (2021) (PubMed).: "Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle." in: Scientific reports, Vol. 9, Issue 1, pp. 2320, (2020) (PubMed).
: "CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism." in: Frontiers in immunology, Vol. 11, pp. 148, (2020) (PubMed).
: "In Vivo Two-Photon Fluorescence Imaging of the Activity of the Inflammatory Biomarker LTA4H in a Mouse Pneumonia Model." in: Analytical chemistry, Vol. 90, Issue 10, pp. 6020-6027, (2019) (PubMed).
: "NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury." in: Nature communications, Vol. 8, Issue 1, pp. 950, (2018) (PubMed).
: "A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer." in: Nature communications, Vol. 8, Issue 1, pp. 1390, (2018) (PubMed).
: "Lactulose attenuates METH-induced neurotoxicity by alleviating the impaired autophagy, stabilizing the perturbed antioxidant system and suppressing apoptosis in rat striatum." in: Toxicology letters, Vol. 289, pp. 107-113, (2018) (PubMed).
: "A critical role of hepatitis B virus polymerase in cirrhosis, hepatocellular carcinoma, and steatosis." in: FEBS open bio, Vol. 8, Issue 1, pp. 130-145, (2018) (PubMed).
: "Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats." in: Biochimica et biophysica acta, Vol. 1861, Issue 7, pp. 1801-1812, (2017) (PubMed).
: "Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006426, (2017) (PubMed).
Synonyms and alternative names related to ALT
glutamic--pyruvic transaminase (GPT), glutamic-pyruvate transaminase (alanine aminotransferase) (GPT), glutamic--pyruvic transaminase (Gpt), alanine aminotransferase (Tb927.1.3950), alanine aminotransferase (ANI_1_368094), alanine aminotransferase (AOR_1_284154), alanine aminotransferase (ALAT_1), alanine aminotransferase 1 (ALAAT1), alanine aminotransferase (EHI_159710), alanine aminotransferase (EHI_096750), alanine aminotransferase 1 (LOC5572541), alanine aminotransferase (ALAT), alanine aminotransferase (AAT2), glutamic pyruvic transaminase, soluble (Gpt), dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (Dpagt1), alanine aminotransferase 2-like (LOC100537633), Alanine aminotransferase 1, mitochondrial (AlaAT1), 24.t00016, 233.t00009, 1300007J06Rik, 2310022B03Rik, AAT1, ALANINE AMINOTRANSFERAS, alanine aminotransferas, ALT, ALT1, An11g02620, AO090003000164, AtAlaAT1, AtAlaATc, AU021132, Dpagt2, Gnpta, GPT, gpt, Gpt-1, GPT1, Gpt1, T13M22.3, T13M22_3Protein level used designations for ALT
- GPT 1
- alanine aminotransferase 1
- glutamate pyruvate transaminase 1
- glutamic--alanine transaminase 1
- glutamic--pyruvic transaminase 1
- glutamic-alanine transaminase 1
- glutamic-pyruvate transaminase (alanine aminotransferase)
- ALT1
- glutamic pyruvate transaminase
- glutamic pyruvic transaminase (alanine aminotrasferase)
- glutamic pyruvic transaminase 1, soluble
- alanine aminotransferase
- alanine aminotransferase 1-like
- G1PT
- N-acetylglucosamine-1-phosphate transferase
- UDP-N-acetylglucosamine lysosomal enzyme N-acetylglucosamine phosphotransferase
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- dolichyl-phosphate alpha-N-acetylglucosaminephosphotransferase 2
- glcNAc-1-P transferase
- glutamic pyruvic transaminase, soluble
- alanine aminotransferase 2-like
- glutamic--pyruvic transaminase
- Alanine-2-oxoglutarate aminotransferase 4
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