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alpha KGDHC Products

(alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009].

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Featured alpha KGDHC Categories

alpha KGDHC Antibodies

High quality antibodies with extensive validation data.

alpha KGDHC ELISA Kits

Reliable ELISA kits for a wide range of species.

alpha KGDHC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended alpha KGDHC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN6145003
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN2856043
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7011083
Quantity 60 μL
Datasheet Datasheet

Recommended alpha KGDHC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964745
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964746
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964744
Quantity 96 tests
Datasheet Datasheet

Recommended alpha KGDHC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408444
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
Cat. No. ABIN1945412
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398821
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our alpha KGDHC products

Stein, Jadiya, Zhang, McLendon, Abouassaly, Witmer, Anderson, Elrod, Boudreau: "Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency." in: Cell reports, Vol. 23, Issue 13, pp. 3710-3720.e8, (2018) (PubMed).

Chaumeil, Larson, Woods, Cai, Eriksson, Robinson, Lupo, Vigneron, Nelson, Pieper, Phillips, Ronen: "Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma." in: Cancer research, Vol. 74, Issue 16, pp. 4247-57, (2014) (PubMed).

Synonyms and alternative names related to alpha KGDHC

oxoglutarate dehydrogenase (OGDH), oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (Ogdh), oxoglutarate dehydrogenase (Ogdh), 2210403E04Rik, 2210412K19Rik, AA409584, AKGDH, d1401, E1k, mKIAA4192, OGDC

Protein level used designations for alpha KGDHC

  • 2-oxoglutarate dehydrogenase, mitochondrial
  • 2-oxoglutarate dehydrogenase complex component E1
  • OGDC-E1
  • oxoglutarate decarboxylase
  • oxoglutarate dehydrogenase (succinyl-transferring)
  • 2-oxoglutarate dehydrogenase E1 component, mitochondrial
  • alpha-ketoglutarate dehydrogenase
  • oxoglutarate dehydrogenase (lipoamide)
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