alpha KGDHC Products
(alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
Categories
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009].
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Featured alpha KGDHC Categories
alpha KGDHC Antibodies
High quality antibodies with extensive validation data.
alpha KGDHC ELISA Kits
Reliable ELISA kits for a wide range of species.
alpha KGDHC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended alpha KGDHC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (5)
Cat. No.
ABIN6145003
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2856043
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7011083
Quantity
60 μL
Datasheet
Datasheet
Recommended alpha KGDHC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964745
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964746
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964744
Quantity
96 tests
Datasheet
Datasheet
Recommended alpha KGDHC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408444
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293T Cells
Validations
Cat. No.
ABIN1945412
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398821
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our alpha KGDHC products
: "Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency." in: Cell reports, Vol. 23, Issue 13, pp. 3710-3720.e8, (2018) (PubMed).: "Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma." in: Cancer research, Vol. 74, Issue 16, pp. 4247-57, (2014) (PubMed).
Synonyms and alternative names related to alpha KGDHC
oxoglutarate dehydrogenase (OGDH), oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (Ogdh), oxoglutarate dehydrogenase (Ogdh), 2210403E04Rik, 2210412K19Rik, AA409584, AKGDH, d1401, E1k, mKIAA4192, OGDCProtein level used designations for alpha KGDHC
- 2-oxoglutarate dehydrogenase, mitochondrial
- 2-oxoglutarate dehydrogenase complex component E1
- OGDC-E1
- oxoglutarate decarboxylase
- oxoglutarate dehydrogenase (succinyl-transferring)
- 2-oxoglutarate dehydrogenase E1 component, mitochondrial
- alpha-ketoglutarate dehydrogenase
- oxoglutarate dehydrogenase (lipoamide)
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