ALOX5AP Products
(Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
Categories
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
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Featured ALOX5AP Categories
ALOX5AP Antibodies
High quality antibodies with extensive validation data.
ALOX5AP ELISA Kits
Reliable ELISA kits for a wide range of species.
ALOX5AP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ALOX5AP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS, IF
Validations
- (7)
Cat. No.
ABIN185249
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN185717
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN392385
Quantity
400 μL
Datasheet
Datasheet
Recommended ALOX5AP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964996
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730404
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1122348
Quantity
96 tests
Datasheet
Datasheet
Recommended ALOX5AP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344923
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096858
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133653
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ALOX5AP products
: "The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211943, (2019) (PubMed).: "Impact of Arachidonic Acid and the Leukotriene Signaling Pathway on Vasculogenesis of Mouse Embryonic Stem Cells." in: Cells, tissues, organs, Vol. 201, Issue 5, pp. 319-32, (2016) (PubMed).
: "ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance." in: Diabetes, Vol. 65, Issue 8, pp. 2139-50, (2016) (PubMed).
: "Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study." in: Atherosclerosis, Vol. 239, Issue 2, pp. 528-38, (2015) (PubMed).
: "Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123256, (2015) (PubMed).
: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).
: "The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells." in: Cardiovascular research, Vol. 86, Issue 1, pp. 37-44, (2010) (PubMed).
: "Celecoxib inhibits 5-lipoxygenase." in: Biochemical pharmacology, Vol. 76, Issue 7, pp. 862-72, (2008) (PubMed).
: "ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance." in: International journal of obesity (2005), Vol. 30, Issue 3, pp. 447-52, (2006) (PubMed).
: "The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. ..." in: Nature genetics, Vol. 36, Issue 3, pp. 233-9, (2004) (PubMed).
Synonyms and alternative names related to ALOX5AP
arachidonate 5-lipoxygenase-activating protein (alox5ap), arachidonate 5-lipoxygenase activating protein (ALOX5AP), arachidonate 5-lipoxygenase activating protein (alox5ap), arachidonate 5-lipoxygenase activating protein (Alox5ap), al5ap, Alox5ap, ALOX5AP, fj65d02, flap, Flap, FLAP, wu:fj65d02, zgc:63982Protein level used designations for ALOX5AP
- arachidonate 5-lipoxygenase-activating protein
- Arachidonate 5-lipoxygenase-activating protein
- MK-886-binding protein
- arachidonate 5 lipoxygenase activating protein
- 5-lipoxygenase-activating protein FLAP
- FLAP
- arachidonate 5-lipoxygenase activating protein
- 5-lipoxygenase-activating protein
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