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ALDOB Products

(Aldolase B, Fructose-Bisphosphate (ALDOB))

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Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008].

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Featured ALDOB Categories

ALDOB Antibodies

High quality antibodies with extensive validation data.

ALDOB ELISA Kits

Reliable ELISA kits for a wide range of species.

ALDOB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALDOB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (2)
  • (7)
Cat. No. ABIN2855024
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7238519
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1678634
Quantity 100 μg
Datasheet Datasheet

Recommended ALDOB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953602
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953603
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674805
Quantity 96 tests
Datasheet Datasheet

Recommended ALDOB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121788
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344857
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344859
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ALDOB products

Chen, Lin, Chen, Cheng, Cheng, Imai et al.: "Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass ..." in: PLoS ONE, Vol. 15, Issue 1, pp. e0227838, (2020) (PubMed).

Kampf, Mardinoglu, Fagerberg, Hallström, Edlund, Lundberg, Pontén, Nielsen, Uhlen: "The human liver-specific proteome defined by transcriptomics and antibody-based profiling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 7, pp. 2901-14, (2014) (PubMed).

Dawson, Biggar, Storey: "Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure." in: PLoS ONE, Vol. 8, Issue 7, pp. e68830, (2014) (PubMed).

Walmsley, Freund, Curthoys: "Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule." in: American journal of physiology. Renal physiology, Vol. 302, Issue 11, pp. F1465-77, (2012) (PubMed).

Merkulova, Hurtado-Lorenzo, Hosokawa, Zhuang, Brown, Ausiello, Marshansky: "Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution." in: American journal of physiology. Cell physiology, Vol. 300, Issue 6, pp. C1442-55, (2011) (PubMed).

Synonyms and alternative names related to ALDOB

aldolase B (xaldb), aldolase, fructose-bisphosphate B (aldob), aldolase, fructose-bisphosphate B S homeolog (aldob.S), aldolase, fructose-bisphosphate B (ALDOB), aldolase b, fructose-bisphosphate (aldob), aldolase B, fructose-bisphosphate (Aldob), aldolase, fructose-bisphosphate B (Aldob), aldb, ALDB, Aldo-2, aldo2, ALDO2, Aldo2, ALDOB, aldob, BC016435, fb25f09, LIV10, wu:fb25f09, xaldb

Protein level used designations for ALDOB

  • aldolase B, fructose-bisphosphate
  • Fructose-bisphosphate aldolase B
  • fructose-bisphosphate aldolase B-like
  • aldolase 2
  • aldolase B, fructose-bisphosphatase
  • fructose-bisphosphate aldolase B
  • liver-type aldolase
  • fructose 1,6, bisphosphate aldolase
  • aldolase 2, B isoform
  • Aldolase B fructose-biphosphate
  • Aldolase B, fructose-biphosphate
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