ALDOB Products
(Aldolase B, Fructose-Bisphosphate (ALDOB))
Categories
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008].
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Featured ALDOB Categories
ALDOB Antibodies
High quality antibodies with extensive validation data.
ALDOB ELISA Kits
Reliable ELISA kits for a wide range of species.
ALDOB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ALDOB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN2855024
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7238519
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1678634
Quantity
100 μg
Datasheet
Datasheet
Recommended ALDOB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953603
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674805
Quantity
96 tests
Datasheet
Datasheet
Recommended ALDOB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121788
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344857
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344859
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ALDOB products
: "Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass ..." in: PLoS ONE, Vol. 15, Issue 1, pp. e0227838, (2020) (PubMed).: "The human liver-specific proteome defined by transcriptomics and antibody-based profiling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 7, pp. 2901-14, (2014) (PubMed).
: "Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure." in: PLoS ONE, Vol. 8, Issue 7, pp. e68830, (2014) (PubMed).
: "Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule." in: American journal of physiology. Renal physiology, Vol. 302, Issue 11, pp. F1465-77, (2012) (PubMed).
: "Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution." in: American journal of physiology. Cell physiology, Vol. 300, Issue 6, pp. C1442-55, (2011) (PubMed).
Synonyms and alternative names related to ALDOB
aldolase B (xaldb), aldolase, fructose-bisphosphate B (aldob), aldolase, fructose-bisphosphate B S homeolog (aldob.S), aldolase, fructose-bisphosphate B (ALDOB), aldolase b, fructose-bisphosphate (aldob), aldolase B, fructose-bisphosphate (Aldob), aldolase, fructose-bisphosphate B (Aldob), aldb, ALDB, Aldo-2, aldo2, ALDO2, Aldo2, ALDOB, aldob, BC016435, fb25f09, LIV10, wu:fb25f09, xaldbProtein level used designations for ALDOB
- aldolase B, fructose-bisphosphate
- Fructose-bisphosphate aldolase B
- fructose-bisphosphate aldolase B-like
- aldolase 2
- aldolase B, fructose-bisphosphatase
- fructose-bisphosphate aldolase B
- liver-type aldolase
- fructose 1,6, bisphosphate aldolase
- aldolase 2, B isoform
- Aldolase B fructose-biphosphate
- Aldolase B, fructose-biphosphate
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