ALAS1 Products
(Aminolevulinate, delta-, Synthase 1 (ALAS1))
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This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme\; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
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Featured ALAS1 Categories
ALAS1 Antibodies
High quality antibodies with extensive validation data.
ALAS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ALAS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ALAS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN559839
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7142600
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6259873
Quantity
100 μL
Datasheet
Datasheet
Recommended ALAS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953665
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN1742702
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773606
Quantity
96 tests
Datasheet
Datasheet
Recommended ALAS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344797
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5505552
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ALAS1 products
: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).: "Nuclear receptor 5A (NR5A) family regulates 5-aminolevulinic acid synthase 1 (ALAS1) gene expression in steroidogenic cells." in: Endocrinology, Vol. 153, Issue 11, pp. 5522-34, (2012) (PubMed).
: "Gonadotropin regulation of genes differentially expressed in response to PKCzeta inhibitor during ovulation in the rat." in: Life sciences, Vol. 85, Issue 3-4, pp. 153-60, (2009) (PubMed).
: "PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 2, pp. E463-74, (2008) (PubMed).
: "Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin." in: Molecular and cellular biochemistry, Vol. 319, Issue 1-2, pp. 153-61, (2008) (PubMed).
Synonyms and alternative names related to ALAS1
5'-aminolevulinate synthase 1 (ALAS1), aminolevulinic acid synthase 1 (Alas1), 5'-aminolevulinate synthase 1 (Alas1), 5'-aminolevulinate synthase 1 (alas1), 5'-aminolevulinate synthase 1 (alas1.S), alanyl-tRNA synthetase protein (alaS1), aminolevulinate, delta-, synthase 1 (alas1), ALAS, Alas-1, Alas-h, ALAS-H, ALAS-N, ALAS1, ALAS3, ALASH, ALASN, MIG4, wu:fb58d01, wu:fi12g09Protein level used designations for ALAS1
- 5-aminolevulinate synthase, nonspecific, mitochondrial
- 5-aminolevulinic acid synthase 1
- ALAS-H
- delta-ALA synthase 1
- delta-aminolevulinate synthase 1
- migration-inducing protein 4
- aminolevulinate synthase H
- succinyl-CoA: glycine C-succinyl transferase
- 5-aminolevulinate synthase 1
- ALA-S
- ALAS-N
- aminolevulinic acid synthase 1
- delta-ALA synthetase
- aminolevulinate, delta, synthase 1
- delta-ALA synthetase 1
- ALA-synthase
- aminolevulinate, delta-, synthase 1
- Delta-ALA synthetase
- 5-aminolevulinate synthase, nonspecific, mitochondrial-like
- 5-aminolevulinic acid synthase
- alanyl-tRNA synthetase protein
- aminolevulinate synthase 1
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