ALAD Products
(Aminolevulinate Dehydratase (ALAD))
Categories
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway\; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. [provided by RefSeq, Jul 2008].
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Featured ALAD Categories
ALAD Antibodies
High quality antibodies with extensive validation data.
ALAD ELISA Kits
Reliable ELISA kits for a wide range of species.
ALAD Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ALAD Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN390809
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN513229
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN513228
Quantity
50 μg
Datasheet
Datasheet
Recommended ALAD ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964796
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953663
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953664
Quantity
96 tests
Datasheet
Datasheet
Recommended ALAD Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121814
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344795
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344793
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ALAD products
: "Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity." in: Obesity (Silver Spring, Md.), Vol. 25, Issue 10, pp. 1723-1733, (2018) (PubMed).: "Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy." in: Cancer research, Vol. 71, Issue 18, pp. 6040-50, (2011) (PubMed).
: "Single amino acid mutations alter the distribution of human porphobilinogen synthase quaternary structure isoforms (morpheeins)." in: The Journal of biological chemistry, Vol. 281, Issue 10, pp. 6682-90, (2006) (PubMed).
Synonyms and alternative names related to ALAD
delta-aminolevulinate dehydratase (hemB), aminolevulinate dehydratase (ALAD), delta-aminolevulinic acid dehydratase (PBGS), delta-aminolevulinic acid dehydratase (STY0404), delta-aminolevulinic acid dehydratase (hemB), delta-aminolevulinic acid dehydratase (SAS1597), delta-aminolevulinic acid dehydratase (SACI_RS03725), delta-aminolevulinic acid dehydratase (ALAD), Delta-aminolevulinic acid dehydratase (hemB), delta-aminolevulinic acid dehydratase (PAAG_00299), delta-aminolevulinic acid dehydratase (VDBG_00315), delta-aminolevulinic acid dehydratase (HPPC_00830), delta-aminolevulinic acid dehydratase (MGYG_01952), Delta-aminolevulinic acid dehydratase (hem2), aminolevulinate dehydratase L homeolog (alad.L), aminolevulinate dehydratase (Alad), aminolevulinate dehydratase (alad), aminolevulinate, delta-, dehydratase (Alad), ALAD, ALADH, ALADR, aminolevulinatedelta-dehydratase, DDBDRAFT_0190269, DDBDRAFT_0231415, DDB_0190269, DDB_0231415, Lv, ncf, PBGS, zgc:110219Protein level used designations for ALAD
- porphobilinogen synthase
- aminolevulinate, delta-, dehydratase
- delta-aminolevulinic acid dehydratase
- Delta-aminolevulinic acid dehydratase
- aminolevulinate dehydratase
- delta-aminolevulinic acid dehydratase-like
- ALADH
- delta - aminolevulinic acid dehydratase
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