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ALAD Products

(Aminolevulinate Dehydratase (ALAD))

Categories

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway\; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. [provided by RefSeq, Jul 2008].

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Featured ALAD Categories

ALAD Antibodies

High quality antibodies with extensive validation data.

ALAD ELISA Kits

Reliable ELISA kits for a wide range of species.

ALAD Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALAD Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN390809
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN513229
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN513228
Quantity 50 μg
Datasheet Datasheet

Recommended ALAD ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964796
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953663
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953664
Quantity 96 tests
Datasheet Datasheet

Recommended ALAD Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121814
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344795
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344793
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ALAD products

Moreno-Navarrete, Rodríguez, Ortega, Becerril, Girones, Sabater-Masdeu, Latorre, Ricart, Frühbeck, Fernández-Real: "Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity." in: Obesity (Silver Spring, Md.), Vol. 25, Issue 10, pp. 1723-1733, (2018) (PubMed).

Anand, Wilson, Hasan, Maytin: "Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy." in: Cancer research, Vol. 71, Issue 18, pp. 6040-50, (2011) (PubMed).

Tang, Breinig, Stith, Mischel, Tannir, Kokona, Fairman, Jaffe: "Single amino acid mutations alter the distribution of human porphobilinogen synthase quaternary structure isoforms (morpheeins)." in: The Journal of biological chemistry, Vol. 281, Issue 10, pp. 6682-90, (2006) (PubMed).

Synonyms and alternative names related to ALAD

delta-aminolevulinate dehydratase (hemB), aminolevulinate dehydratase (ALAD), delta-aminolevulinic acid dehydratase (PBGS), delta-aminolevulinic acid dehydratase (STY0404), delta-aminolevulinic acid dehydratase (hemB), delta-aminolevulinic acid dehydratase (SAS1597), delta-aminolevulinic acid dehydratase (SACI_RS03725), delta-aminolevulinic acid dehydratase (ALAD), Delta-aminolevulinic acid dehydratase (hemB), delta-aminolevulinic acid dehydratase (PAAG_00299), delta-aminolevulinic acid dehydratase (VDBG_00315), delta-aminolevulinic acid dehydratase (HPPC_00830), delta-aminolevulinic acid dehydratase (MGYG_01952), Delta-aminolevulinic acid dehydratase (hem2), aminolevulinate dehydratase L homeolog (alad.L), aminolevulinate dehydratase (Alad), aminolevulinate dehydratase (alad), aminolevulinate, delta-, dehydratase (Alad), ALAD, ALADH, ALADR, aminolevulinatedelta-dehydratase, DDBDRAFT_0190269, DDBDRAFT_0231415, DDB_0190269, DDB_0231415, Lv, ncf, PBGS, zgc:110219

Protein level used designations for ALAD

  • porphobilinogen synthase
  • aminolevulinate, delta-, dehydratase
  • delta-aminolevulinic acid dehydratase
  • Delta-aminolevulinic acid dehydratase
  • aminolevulinate dehydratase
  • delta-aminolevulinic acid dehydratase-like
  • ALADH
  • delta - aminolevulinic acid dehydratase
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