AKR1D1 Products
(Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
Categories
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010].
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Featured AKR1D1 Categories
AKR1D1 Antibodies
High quality antibodies with extensive validation data.
AKR1D1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AKR1D1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN562993
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7235767
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7142330
Quantity
100 μg
Datasheet
Datasheet
Recommended AKR1D1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6234515
Quantity
96 tests
Datasheet
Datasheet
Recommended AKR1D1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1344768
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121785
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344770
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our AKR1D1 products
: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).: "Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1538-47, (2013) (PubMed).
Synonyms and alternative names related to AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase-like (LOC491379), aldo-keto reductase family 1 member D1 (AKR1D1), aldo-keto reductase family 1, member D1 (Akr1d1), aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (AKR1D1), 3o5bred, CBAS2, SRD5B1Protein level used designations for AKR1D1
- 3-oxo-5-beta-steroid 4-dehydrogenase
- delta 4-3-ketosteroid-5-beta-reductase
- delta(4)-3-ketosteroid 5-beta-reductase
- delta(4)-3-oxosteroid 5-beta-reductase
- steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
- aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- aldo-keto reductase family 1 member D1
- delta4-3-oxosteroid 5beta-reductase
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