AKR1C4 Products
(Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
Categories
This gene encodes a member of the aldo\\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].
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Featured AKR1C4 Categories
AKR1C4 Antibodies
High quality antibodies with extensive validation data.
AKR1C4 ELISA Kits
Reliable ELISA kits for a wide range of species.
AKR1C4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AKR1C4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN560358
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN514377
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN514376
Quantity
50 μg
Datasheet
Datasheet
Recommended AKR1C4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964709
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4881789
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384210
Quantity
96 tests
Datasheet
Datasheet
Recommended AKR1C4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121778
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344762
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1095981
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our AKR1C4 products
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).: "Regulation of human 3 alpha-hydroxysteroid dehydrogenase (AKR1C4) expression by the liver X receptor alpha." in: Molecular pharmacology, Vol. 73, Issue 2, pp. 607-12, (2008) (PubMed).
: "Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study." in: Breast cancer research : BCR, Vol. 7, Issue 3, pp. R336-44, (2005) (PubMed).
Synonyms and alternative names related to AKR1C4
aldo-keto reductase family 1 member C4 (AKR1C4), 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRAProtein level used designations for AKR1C4
- 3-alpha-HSD1
- aldo-keto reductase family 1 member C4
- chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4
- dihydrodiol dehydrogenase isozyme DD4
- type I 3-alpha-hydroxysteroid dehydrogenase
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