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AKAP9 Products

(A Kinase (PRKA) Anchor Protein (Yotiao) 9 (AKAP9))

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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008].

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Featured AKAP9 Categories

AKAP9 Antibodies

High quality antibodies with extensive validation data.

Recommended AKAP9 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
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Cat. No. ABIN7142915
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF
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  • (2)
Cat. No. ABIN185354
Quantity 100 μg
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Reactivity Human
Application ELISA, WB, IF
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Cat. No. ABIN948895
Quantity 100 μg
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Recommended AKAP9 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1344736
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AKAP9 products

Gorshkov, Mehta, Ramamurthy, Ronnett, Zhou, Zhang: "AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons." in: Nature chemical biology, Vol. 13, Issue 4, pp. 425-431, (2017) (PubMed).

Oldenburger, Poppinga, Kos, de Bruin, Rijks, Heijink, Timens, Meurs, Maarsingh, Schmidt: "A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke." in: American journal of physiology. Cell physiology, Vol. 306, Issue 6, pp. C585-97, (2014) (PubMed).

Sato, Hayashi, Amano, Takahashi, Yonemura, Hayashi, Hirose, Ohno, Suzuki: "MTCL1 crosslinks and stabilizes non-centrosomal microtubules on the Golgi membrane." in: Nature communications, Vol. 5, pp. 5266, (2014) (PubMed).

Christian, Szaszák, Friedl, Drewianka, Lorenz, Goncalves, Furkert, Vargas, Schmieder, Götz, Zühlke, Moutty, Göttert, Joshi, Reif, Haase, Morano, Grossmann, Klukovits, Verli, Gáspár, Noack, Bergmann et al.: "Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. ..." in: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9079-96, (2011) (PubMed).

Frank, Wiestler, Kropp, Hemminki, Spurdle, Sutter, Wappenschmidt, Chen, Beesley, Hopper, Meindl, Kiechle, Slanger, Bugert, Schmutzler, Bartram, Flesch-Janys, Mutschelknauss, Ashton, Salazar, Webb et al.: "Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. ..." in: Journal of the National Cancer Institute, Vol. 100, Issue 6, pp. 437-42, (2008) (PubMed).

Ciampi, Knauf, Kerler, Gandhi, Zhu, Nikiforova, Rabes, Fagin, Nikiforov: "Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer." in: The Journal of clinical investigation, Vol. 115, Issue 1, pp. 94-101, (2005) (PubMed).

Westphal, Tavalin, Lin, Alto, Fraser, Langeberg, Sheng, Scott: "Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex." in: Science (New York, N.Y.), Vol. 285, Issue 5424, pp. 93-6, (1999) (PubMed).

Witczak, Skålhegg, Keryer, Bornens, Taskén, Jahnsen, Orstavik: "Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450." in: The EMBO journal, Vol. 18, Issue 7, pp. 1858-68, (1999) (PubMed).

Lin, Wyszynski, Madhavan, Sealock, Kim, Sheng: "Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 6, pp. 2017-27, (1998) (PubMed).

Synonyms and alternative names related to AKAP9

A-kinase anchoring protein 9 (AKAP9), A kinase (PRKA) anchor protein (yotiao) 9 (Akap9), A-kinase anchoring protein 9 (Akap9), A kinase (PRKA) anchor protein 9 (akap9), A-kinase anchoring protein 9 (akap9), A kinase (PRKA) anchor protein (yotiao) 9 (AKAP9), A-kinase anchoring protein AKAP120 (CpipJ_CPIJ006715), A-kinase anchoring protein AKAP120 (CpipJ_CPIJ017436), 5730481H23Rik, AKAP-9, AKAP9, AKAP120, AKAP350, akap350, AKAP450, akap450, AW545847, C79026, CG-NAP, Gisp, HYPERION, hyperion, LQT11, mKIAA0803, MU-RMS-40.16A, PPP1R45, PRKA9, prka9, wu:fj02h02, YOTIAO, Yotiao, yotiao

Protein level used designations for AKAP9

  • A-kinase anchor protein 350 kDa
  • A-kinase anchor protein 450 kDa
  • A-kinase anchor protein 9
  • AKAP 120-like protein
  • AKAP9-BRAF fusion protein
  • centrosome- and Golgi-localized PKN-associated protein
  • kinase N-associated protein
  • protein hyperion
  • protein kinase A anchoring protein 9
  • protein phosphatase 1, regulatory subunit 45
  • protein yotiao
  • protein kinase A-anchoring protein 9
  • GABA-B receptor-interacting scaffolding protein
  • hyperion protein, 419 kD isoform
  • A kinase (PRKA) anchor protein (yotiao) 9
  • a-kinase anchor protein 9
  • a-kinase anchor protein 9-like
  • A kinase (PRKA) anchor protein 9
  • A-kinase anchoring protein AKAP120
  • A-kinase anchor protein 120 kDa
  • AKAP 120
  • AKAP-9
  • PRKA9
  • myocyte A kinase anchor protein
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