AIM2 Products
(Absent in Melanoma 2 (AIM2))
Categories
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008].
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Featured AIM2 Categories
AIM2 Antibodies
High quality antibodies with extensive validation data.
AIM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
AIM2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AIM2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (6)
Cat. No.
ABIN5542273
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (4)
Cat. No.
ABIN7441334
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IF
Validations
- (5)
Cat. No.
ABIN3029828
Quantity
0.4 mL
Datasheet
Datasheet
Recommended AIM2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6953386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951065
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1138535
Quantity
96 tests
Datasheet
Datasheet
Recommended AIM2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1788691
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408477
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
Cat. No.
ABIN7317509
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our AIM2 products
: "A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 24, Issue 6, pp. 934-953, (2018) (PubMed).: "Pyroptotic neuronal cell death mediated by the AIM2 inflammasome." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 34, Issue 4, pp. 621-9, (2014) (PubMed).
: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." in: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).
: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." in: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).
: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).
: "Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 1, pp. 394-403, (2011) (PubMed).
: "Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation." in: The Journal of biological chemistry, Vol. 286, Issue 45, pp. 39033-42, (2011) (PubMed).
: "Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 30, Issue 6, pp. 371-80, (2010) (PubMed).
: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." in: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).
: "AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC." in: Nature, Vol. 458, Issue 7237, pp. 514-8, (2009) (PubMed).
Synonyms and alternative names related to AIM2
absent in melanoma 2 (AIM2), absent in melanoma 2 (Aim2), AIM2, Gm1313, Ifi210, PYHIN4Protein level used designations for AIM2
- absent in melanoma 2
- interferon-inducible protein AIM2-like
- interferon-inducible protein AIM2
- ifi-210
- interferon-inducible protein 210
- interferon-inducible protein p210
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