AICDA Products
(Activation-Induced Cytidine Deaminase (AICDA))
Categories
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009].
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Featured AICDA Categories
AICDA Antibodies
High quality antibodies with extensive validation data.
AICDA ELISA Kits
Reliable ELISA kits for a wide range of species.
AICDA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AICDA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (4)
Cat. No.
ABIN2855890
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, EIA
Validations
- (1)
- (3)
Cat. No.
ABIN499233
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (2)
Cat. No.
ABIN3181420
Quantity
100 μL
Datasheet
Datasheet
Recommended AICDA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953423
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593414
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212552
Quantity
96 tests
Datasheet
Datasheet
Recommended AICDA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN1098741
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344654
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2127824
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AICDA products
: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." in: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).: "Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection." in: Virology, Vol. 484, pp. 323-333, (2015) (PubMed).
: "Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5751-63, (2013) (PubMed).
: "Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients." in: Clinical immunology (Orlando, Fla.), Vol. 135, Issue 3, pp. 459-65, (2010) (PubMed).
: "Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 5, pp. 1616-20, (2007) (PubMed).
: "Regulation of AID expression in the immune response." in: The Journal of experimental medicine, Vol. 204, Issue 5, pp. 1145-56, (2007) (PubMed).
: "AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner." in: Molecular and cellular biology, Vol. 27, Issue 1, pp. 20-30, (2006) (PubMed).
: "The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4378-85, (2006) (PubMed).
: "Advantages and disadvantages of cytidine deamination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, (2004) (PubMed).
: "Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas." in: Blood, Vol. 101, Issue 9, pp. 3574-80, (2003) (PubMed).
Synonyms and alternative names related to AICDA
activation induced cytidine deaminase (AICDA), activation-induced cytidine deaminase (Aicda), activation-induced cytidine deaminase (aicda), activation-induced cytidine deaminase L homeolog (aicda.L), activation induced cytidine deaminase (aicda), AICDA, AID, Aid, aid, ARP2, Arp2, arp2, CDA2, cda2, HIGM2, higm2, xlaidProtein level used designations for AICDA
- cytidine aminohydrolase
- integrated into Burkitt's lymphoma cell line Ramos
- single-stranded DNA cytosine deaminase
- activation induced deaminase
- activation-induced cytidine deaminase
- aid
- activation induced cytidine deaminase
- activation-induced deaminase
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