AGT Products
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Categories
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008].
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Featured AGT Categories
AGT Antibodies
High quality antibodies with extensive validation data.
AGT ELISA Kits
Reliable ELISA kits for a wide range of species.
AGT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AGT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN2855709
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432628
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432631
Quantity
100 μL
Datasheet
Datasheet
Recommended AGT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN626653
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN509855
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN627484
Quantity
96 tests
Datasheet
Datasheet
Recommended AGT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344600
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344602
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344604
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our AGT products
: "Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction." in: Environmental toxicology and pharmacology, Vol. 80, pp. 103501, (2021) (PubMed).: "Protein malnutrition impairs bone marrow endothelial cells affecting hematopoiesis." in: Clinical nutrition (Edinburgh, Scotland), Vol. 39, Issue 5, pp. 1551-1559, (2020) (PubMed).
: "Isoflavone Ameliorated Oxidative Stress and Vascular Damages in Nicotine-Administrated Mice." in: Journal of oleo science, Vol. 68, Issue 12, pp. 1241-1249, (2019) (PubMed).
: "Quantitation of Total and Free Thiol Angiotensinogen as a Prognostic Marker for Preeclampsia." in: Methods in molecular biology (Clifton, N.J.), Vol. 1967, pp. 285-293, (2019) (PubMed).
: "Role of (pro)renin receptor in albumin overload-induced nephropathy in rats." in: American journal of physiology. Renal physiology, Vol. 315, Issue 6, pp. F1759-F1768, (2018) (PubMed).
: "Relationship between blood pressure variability and renal activity of the renin-angiotensin system." in: Journal of human hypertension, Vol. 30, Issue 5, pp. 297-302, (2016) (PubMed).
: "Lipid disorder and intrahepatic renin-angiotensin system activation synergistically contribute to non-alcoholic fatty liver disease." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 36, Issue 10, pp. 1525-34, (2016) (PubMed).
: "Induction of multiple ovulation via modulation of angiotensin II receptors in in vitro ovarian follicle culture models." in: Journal of tissue engineering and regenerative medicine, (2016) (PubMed).
: "Interrelationship between angiogenesis, inflammation and oxidative stress in Indian patients with multiple myeloma." in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, Vol. 18, Issue 2, pp. 132-7, (2016) (PubMed).
: "Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells." in: Acta pharmacologica Sinica, Vol. 38, Issue 1, pp. 41-55, (2016) (PubMed).
Synonyms and alternative names related to AGT
angiotensinogen (AGT), angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (Agt), angiotensinogen (Agt), angiotensinogen (agt), AGT, AI265500, Ang, AngI, AngII, angt, ANGT, ANHU, ANRT, Aogen, PAT, SERPINA8, Serpina8, wu:fb62f06, wu:fj87b02, zgc:111892Protein level used designations for AGT
- alpha-1 antiproteinase, antitrypsin
- angiotensin I
- angiotensin II
- angiotensinogen
- pre-angiotensinogen
- serine (or cysteine) proteinase inhibitor
- serpin A8
- angiotensin ll
- angiotensinogen (PAT)
- zC8A9.1 (angiotensinogen )
- Angiotensinogen
- Serpin A8
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