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AGR2 Products

(Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity).

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Featured AGR2 Categories

AGR2 Antibodies

High quality antibodies with extensive validation data.

AGR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

AGR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AGR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (9)
  • (4)
Cat. No. ABIN564604
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6136646
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7428746
Quantity 100 μL
Datasheet Datasheet

Recommended AGR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
Cat. No. ABIN6953792
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6961987
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN778000
Quantity 96 tests
Datasheet Datasheet

Recommended AGR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7273812
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7273813
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1344592
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AGR2 products

Guo, Chen, Zhu, Yu, Rong, Merugu, Mangukiya, Li: "A humanized monoclonal antibody targeting secreted anterior gradient 2 effectively inhibits the xenograft tumor growth." in: Biochemical and biophysical research communications, Vol. 475, Issue 1, pp. 57-63, (2017) (PubMed).

Guo, Zhu, Yu, Merugu, Mangukiya, Smith, Li, Zhang, Negi, Rong, Cheng, Wu, Li: "Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization." in: Oncogene, Vol. 36, Issue 36, pp. 5098-5109, (2017) (PubMed).

Dong, Wodziak, Lowe: "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8016-27, (2015) (PubMed).

Garczyk, von Stillfried, Antonopoulos, Hartmann, Schrauder, Fasching, Anzeneder, Tannapfel, Ergönenc, Knüchel, Rose, Dahl: "AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122106, (2015) (PubMed).

Riener, Thiesler, Hellerbrand, Amann, Cathomas, Fritzsche, Dahl, Bahra, Weichert, Terracciano, Kristiansen: "Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas." in: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 10, pp. 1722-30, (2014) (PubMed).

Di Maro, Salerno, Unger, Orlandella, Monaco, Chiappetta, Thomas, Oczko-Wojciechowska, Masullo, Jarzab, Santoro, Salvatore: "Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells." in: Molecular cancer, Vol. 13, pp. 160, (2014) (PubMed).

Bergström, Berg, Rodríguez-Piñeiro, Stecher, Johansson, Hansson: "AGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucus." in: PLoS ONE, Vol. 9, Issue 8, pp. e104186, (2014) (PubMed).

Chan, Prassas, Dimitromanolakis, Brand, Serra, Diamandis, Blasutig: "Validation of biomarkers that complement CA19.9 in detecting early pancreatic cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 22, pp. 5787-95, (2014) (PubMed).

Kani, Malihi, Jiang, Wang, Wang, Ruderman, Agus, Mallick, Gross: "Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype." in: The Prostate, Vol. 73, Issue 3, pp. 306-15, (2013) (PubMed).

Makawita, Dimitromanolakis, Soosaipillai, Soleas, Chan, Gallinger, Haun, Blasutig, Diamandis: "Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9." in: BMC cancer, Vol. 13, pp. 404, (2013) (PubMed).

Synonyms and alternative names related to AGR2

anterior gradient 2, protein disulphide isomerase family member (AGR2), anterior gradient 2 (Agr2), anterior gradient 2 (agr2), anterior gradient 3, protein disulphide isomerase family member (agr3), anterior gradient 2, protein disulphide isomerase family member (Agr2), anterior gradient 2, protein disulphide isomerase family member S homeolog (agr2.S), AG2, agr2, agr2-A, Agr2h, bcmp11, GOB-4, Gob-4, HAG-2, hag-3, hag3, mAG-2, MGC89004, PDIA17, wu:fj29g05, XAG-2, XAgr2, zgc:112187

Protein level used designations for AGR2

  • AG-2
  • HPC8
  • anterior gradient homolog 2
  • anterior gradient protein 2 homolog
  • protein disulfide isomerase family A, member 17
  • secreted cement gland homolog
  • secreted cement gland protein XAG-2 homolog
  • anterior gradient 2 homolog
  • protein Gob-4
  • anterior gradient 2 homologue
  • anterior gradient 3
  • cement gland-specific protein CGS
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