AGAP2 Products
(ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
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The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
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Featured AGAP2 Categories
AGAP2 Antibodies
High quality antibodies with extensive validation data.
AGAP2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AGAP2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN570975
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN654901
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN960073
Quantity
100 μg
Datasheet
Datasheet
Recommended AGAP2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6223198
Quantity
96 tests
Datasheet
Datasheet
Recommended AGAP2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344548
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3088375
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135049
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our AGAP2 products
: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." in: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).: "PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16441-51, (2004) (PubMed).
: "Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10774-9, (2004) (PubMed).
: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." in: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).
: "BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta." in: Experimental cell research, Vol. 288, Issue 1, pp. 84-93, (2003) (PubMed).
: "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis." in: Nature neuroscience, Vol. 6, Issue 11, pp. 1153-61, (2003) (PubMed).
: "Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N." in: Cell, Vol. 103, Issue 6, pp. 919-30, (2001) (PubMed).
: "Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling." in: Trends in biochemical sciences, Vol. 25, Issue 10, pp. 489-95, (2000) (PubMed).
Synonyms and alternative names related to AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (agap2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Agap2), CENTG1, Centg1, GGAP2, mKIAA0167, PIKE, Pike, zgc:153779Protein level used designations for AGAP2
- arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
- Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2
- GTP-binding and GTPase activating protein 2
- centaurin, gamma 1
- cnt-g1
- phosphatidylinositol 3-kinase enhancer
- phosphatidylinositol-3-kinase enhancer
- phosphoinositide 3-kinase enhancer
- AGAP-2
- PIKE
- centaurin-gamma-1
- nuclear GTPase PIKE
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