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ADRA2A Products

(Alpha-2A Adrenergic Receptor (ADRA2A))
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons\; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008].

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Featured ADRA2A Categories

ADRA2A Antibodies

High quality antibodies with extensive validation data.

ADRA2A ELISA Kits

Reliable ELISA kits for a wide range of species.

ADRA2A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ADRA2A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN737091
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC, ICC
Validations
  • (3)
Cat. No. ABIN6257667
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3016752
Quantity 100 μL
Datasheet Datasheet

Recommended ADRA2A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964656
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1121223
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1121224
Quantity 96 tests
Datasheet Datasheet

Recommended ADRA2A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1344486
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6117875
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ADRA2A products

Uddin, Mahmood, Ibrahim, Briski: "Sex-Dimorphic Estrogen Receptor Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neuron Adrenergic Receptor Expression in Hypoglycemic Male and Female Rats." in: Brain research, pp. 146311, (2019) (PubMed).

Rosengren, Jokubka, Tojjar, Granhall, Hansson, Li, Nagaraj, Reinbothe, Tuncel, Eliasson, Groop, Rorsman, Salehi, Lyssenko, Luthman, Renström: "Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes." in: Science (New York, N.Y.), Vol. 327, Issue 5962, pp. 217-20, (2010) (PubMed).

Tan, Walwyn, Evans, Xie: "p38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6270-81, (2009) (PubMed).

Park, Nigg, Waldman, Nummy, Huang-Pollock, Rappley, Friderici: "Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD." in: Molecular psychiatry, Vol. 10, Issue 6, pp. 572-80, (2005) (PubMed).

Hein, Altman, Kobilka: "Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission." in: Nature, Vol. 402, Issue 6758, pp. 181-4, (2000) (PubMed).

Synonyms and alternative names related to ADRA2A

adrenoceptor alpha 2A (adra2a), adrenoceptor alpha 2A (ADRA2A), alpha-2A adrenergic receptor-like (LOC100414445), adrenergic receptor, alpha 2a (Adra2a), adrenoceptor alpha 2A (Adra2a), Adra-2, Adra-2a, ADRA2, ADRA2A, ADRA2R, ADRAR, alpha(2A)AR, alpha2-C10, alpha2A, alpha2A-AR, ALPHA2AAR, AW122659, CA2-47, PORA2AR, RATRG20, RG20, ZNF32

Protein level used designations for ADRA2A

  • alpha(2A)AR
  • alpha-2A adrenergic receptor
  • alpha-2A adrenoceptor
  • alpha-2A adrenoreceptor
  • alpha-2AAR
  • alpha2A-adrenergic receptor
  • adrenergic receptor subtype alpha-2A
  • adrenergic, alpha-2A-, receptor
  • alpha-2A-adrenergic receptor
  • adrenergic receptor alpha-2A
  • alpha-2A adrenergic receptor-like
  • subtype alpha2-C10
  • adrenergic alpha 2A, receptor
  • adrenergic, alpha-2, receptor
  • alpha-2-adrenergic receptor
  • alpha-2D adrenergic receptor
  • alpha-2 adrenergic receptor subtype C10
  • alpha-2-adrenergic receptor, platelet type
  • alpha-2AAR subtype C10
  • adrenergic receptor, alpha 2a
  • alpha 2A adrenoceptor
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