ADAMTS13 Products
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].
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Featured ADAMTS13 Categories
ADAMTS13 Antibodies
High quality antibodies with extensive validation data.
ADAMTS13 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAMTS13 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ADAMTS13 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7265440
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7432937
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6259782
Quantity
100 μL
Datasheet
Datasheet
Recommended ADAMTS13 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6953460
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964600
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964599
Quantity
96 tests
Datasheet
Datasheet
Recommended ADAMTS13 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305888
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505139
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392824
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ADAMTS13 products
: "Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney." in: EBioMedicine, Vol. 16, pp. 302-311, (2017) (PubMed).: "The Expression of Tristetraprolin and Its Relationship with Urinary Proteins in Patients with Diabetic Nephropathy." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141471, (2016) (PubMed).
: "Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome." in: Blood, Vol. 122, Issue 8, pp. 1487-93, (2013) (PubMed).
: "The interaction between factor H and Von Willebrand factor." in: PLoS ONE, Vol. 8, Issue 8, pp. e73715, (2013) (PubMed).
: "Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat)." in: The Journal of biological chemistry, Vol. 287, Issue 53, pp. 44361-71, (2012) (PubMed).
: "Detection of a secreted metalloprotease within the nuclei of liver cells." in: Molecular bioSystems, Vol. 7, Issue 6, pp. 2012-8, (2011) (PubMed).
: "Dilated capillaries, disorganized collagen fibers and differential gene expression in periodontal ligaments of hypomorphic fibrillin-1 mice." in: Cell and tissue research, Vol. 341, Issue 3, pp. 381-95, (2010) (PubMed).
: "Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage." in: Blood, Vol. 114, Issue 24, pp. 5102-11, (2009) (PubMed).
: "Fibrinogen-induced endothelin-1 production from endothelial cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 4, pp. C840-7, (2009) (PubMed).
: "Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9531-42, (2008) (PubMed).
Synonyms and alternative names related to ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif 13 (Adamts13), ADAM-TS13, ADAMTS-13, ADAMTS13, C9orf8, Gm710, vWF-CP, VWFCPProtein level used designations for ADAMTS13
- ADAM metallopeptidase with thrombospondin type 1 motif, 13
- A disintegrin and metalloproteinase with thrombospondin motifs 13
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
- vWF-cleaving protease
- von Willebrand factor-cleaving protease
- ADAM-TS 13
- ADAM-TS13
- ADAMTS-13
- ADAMTS13 isoform IAP-b
- vWF-CP mRNA for von Willebrand factor-cleaving
- ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like
- A disintegrin and metalloproteinase with thrombospondin motifs 13-like
- a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
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