ADAM8 Products
(ADAM Metallopeptidase Domain 8 (ADAM8))
Categories
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009].
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Featured ADAM8 Categories
ADAM8 Antibodies
High quality antibodies with extensive validation data.
ADAM8 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAM8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ADAM8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (6)
Cat. No.
ABIN7193315
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
- (1)
Cat. No.
ABIN1866534
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7150062
Quantity
100 μg
Datasheet
Datasheet
Recommended ADAM8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
- (1)
Cat. No.
ABIN415444
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6961974
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953454
Quantity
96 tests
Datasheet
Datasheet
Recommended ADAM8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273801
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7273803
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121692
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ADAM8 products
: "Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans." in: Atherosclerosis, Vol. 286, pp. 163-171, (2019) (PubMed).: "A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer." in: Yonsei medical journal, Vol. 60, Issue 8, pp. 713-719, (2019) (PubMed).
: "miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells." in: Breast cancer research : BCR, Vol. 18, Issue 1, pp. 40, (2016) (PubMed).
: "ADAM8 as a drug target in pancreatic cancer." in: Nature communications, Vol. 6, pp. 6175, (2015) (PubMed).
: "Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 12, pp. 8053-63, (2007) (PubMed).
: "Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 4, pp. 413-22, (2004) (PubMed).
: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).
: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).
: "CD156 (human ADAM8): expression, primary amino acid sequence, and gene location." in: Genomics, Vol. 41, Issue 1, pp. 56-62, (1997) (PubMed).
: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).
Synonyms and alternative names related to ADAM8
ADAM metallopeptidase domain 8 (ADAM8), a disintegrin and metalloproteinase domain 8 (LOC100304737), a disintegrin and metallopeptidase domain 8 (Adam8), ADAM metallopeptidase domain 8a (adam8a), ADAM metallopeptidase domain 8 (Adam8), a disintegrin and metalloproteinase domain 8 (adam8), adam8, ADAM8, CD156, CD156a, E430039A18Rik, MS2, reprolysin, RGD1566394, si:zc217g15.7, zgc:64059Protein level used designations for ADAM8
- a disintegrin and metalloproteinase domain 8
- cell surface antigen MS2
- disintegrin and metalloproteinase domain-containing protein 8
- human leukocyte differentiation antigen
- ADAM 8
- a disintegrin and metalloprotease domain (ADAM) 8
- a disintegrin and metalloprotease domain 8
- macrophage cysteine-rich glycoprotein
- CD156a
- metalloprotease
- ADAM metallopeptidase domain 8
- a disintegrin and metallopeptidase domain 8
- disintegrin and metalloproteinase domain-containing protein 8-like
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