ADAM22 Products
(ADAM Metallopeptidase Domain 22 (ADAM22))
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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010].
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Featured ADAM22 Categories
ADAM22 Antibodies
High quality antibodies with extensive validation data.
ADAM22 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAM22 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ADAM22 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7436768
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN949360
Quantity
50 μg
Datasheet
Datasheet
Recommended ADAM22 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953451
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4881742
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385773
Quantity
96 tests
Datasheet
Datasheet
Recommended ADAM22 Proteins
Latest Publications for our ADAM22 products
: "Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins." in: Scientific reports, Vol. 8, Issue 1, pp. 14838, (2018) (PubMed).: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).
: "The Polarity Protein Pals1 Regulates Radial Sorting of Axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 29, pp. 10474-84, (2015) (PubMed).
: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." in: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).
: "ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 3, pp. 1038-48, (2010) (PubMed).
: "LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 19, pp. 6607-12, (2010) (PubMed).
: "Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy." in: Nature medicine, Vol. 15, Issue 10, pp. 1208-14, (2009) (PubMed).
Synonyms and alternative names related to ADAM22
a disintegrin and metallopeptidase domain 22 (Adam22), ADAM metallopeptidase domain 22 (Adam22), ADAM metallopeptidase domain 22 (ADAM22), ADAM metallopeptidase domain 22 L homeolog (adam22.L), 2900022I03Rik, ADAM 22, AI854032, MDC2, mdc2, mdc11bProtein level used designations for ADAM22
- a disintegrin and metalloprotease domain (ADAM) 22
- disintegrin and metalloproteinase domain-containing protein 22
- a disintegrin and metalloprotease domain 22
- a disintegrin and metalloproteinase domain 22
- metalloproteinase-disintegrin ADAM22-3
- metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
- ADAM 22
- MDC11.2
- metalloprotease-disintegrin MDC11b
- metalloprotease/disintegrin xMDC11.2
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