ADAM17 Products
(ADAM Metallopeptidase Domain 17 (ADAM17))
Categories
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].
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Featured ADAM17 Categories
ADAM17 Antibodies
High quality antibodies with extensive validation data.
ADAM17 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAM17 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ADAM17 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (8)
Cat. No.
ABIN7426310
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA
Validations
- (1)
- (5)
Cat. No.
ABIN563080
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN705671
Quantity
100 μL
Datasheet
Datasheet
Recommended ADAM17 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (5)
Cat. No.
ABIN6730919
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974750
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953448
Quantity
96 tests
Datasheet
Datasheet
Recommended ADAM17 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
- (1)
Cat. No.
ABIN7538118
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121690
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964407
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ADAM17 products
: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." in: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).: "L-Selectin Expression is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia." in: Cytometry. Part B, Clinical cytometry, Vol. 96, Issue 2, pp. 149-157, (2020) (PubMed).
: "PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice." in: Chemico-biological interactions, Vol. 330, pp. 109245, (2020) (PubMed).
: "Metalloproteinases TACE and MMP-9 Differentially Regulate Death Factors on Adult and Neonatal Monocytes After Infection with Escherichia coli." in: International journal of molecular sciences, Vol. 20, Issue 6, (2019) (PubMed).
: "ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes." in: Biomedical research (Tokyo, Japan), Vol. 38, Issue 3, pp. 157-165, (2018) (PubMed).
: "An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans." in: PLoS pathogens, Vol. 14, Issue 4, pp. e1006981, (2018) (PubMed).
: "Reduced neurotrophic factor level is the early event before the functional neuronal deficiency in high-fat diet induced obese mice." in: Metabolic brain disease, Vol. 32, Issue 1, pp. 247-257, (2018) (PubMed).
: "Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways." in: Molecular and cellular biochemistry, Vol. 426, Issue 1-2, pp. 17-26, (2017) (PubMed).
: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).
: "Secretome Signature Identifies ADAM17 as Novel Target for Radiosensitization of Non-Small Cell Lung Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 17, pp. 4428-39, (2016) (PubMed).
Synonyms and alternative names related to ADAM17
ADAM metallopeptidase domain 17 (ADAM17), a disintegrin and metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17b (adam17b), ADAM metallopeptidase domain 17 L homeolog (adam17.L), ADAM metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17a (adam17a), adam17, ADAM18, adam18, CD156B, CD156b, cd156b, CSVP, csvp, fc20b01, NISBD, si:dkey-81b15.2, TACE, Tace, tace, wu:fc20b01, zgc:63886Protein level used designations for ADAM17
- ADAM metallopeptidase domain 18
- TNF-alpha convertase
- TNF-alpha converting enzyme
- disintegrin and metalloproteinase domain-containing protein 17
- snake venom-like protease
- tumor necrosis factor, alpha, converting enzyme
- ADAM 17
- TNF-alpha-converting enzyme
- a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme
- a disintegrin and metalloproteinase domain 17
- a disintegrin and metallopeptidase domain 17
- ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
- a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
- tumor necrosis factor alpha converting enzyme
- ADAM metallopeptidase domain 17
- a disintegrin and metalloprotease domain 17
- disintegrin metalloproteinase
- disintegrin and metalloproteinase domain-containing protein 17-like
- ADAM metallopeptidase domain 17a
- DKEY-174C12.1
- a disintegrin and metalloproteinase domain 17a
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