Apotosis Activator 2
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- Application
- Apoptosis Induction (AI), Cell Culture (CC)
- Purity
- > 98 % by NMR analysis
- Chemical Name
- 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
- Formula
- C15H9NO2Cl2
- Solubility
- Soluble in DMSO or 100% ethanol
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- Comment
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Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome and triggering caspase-9 activation resulting in activated caspase-3. Shows a stronger selectivity for cancer cells than for normal cell lines. Acts in a similar fashion as apoptosis inducer alpha- (trichloromethyl)-4-pyridineethanol (PETCM).
- Restrictions
- For Research Use only
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- Format
- Solid
- Storage
- 4 °C
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- Molecular Weight
- 306.1 g/mol
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