ACVRL1 Products
(Activin A Receptor Type II-Like 1 (ACVRL1))
Categories
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008].
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Featured ACVRL1 Categories
ACVRL1 Antibodies
High quality antibodies with extensive validation data.
ACVRL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ACVRL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACVRL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (4)
- (5)
Cat. No.
ABIN392241
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (7)
Cat. No.
ABIN3029853
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7183058
Quantity
100 μL
Datasheet
Datasheet
Recommended ACVRL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953428
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5510685
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5510686
Quantity
96 tests
Datasheet
Datasheet
Recommended ACVRL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7273821
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320736
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491397
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ACVRL1 products
: "Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis. ..." in: Nature metabolism, Vol. 1, Issue 9, pp. 912-926, (2019) (PubMed).: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." in: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).
: "The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes." in: Cellular & molecular biology letters, Vol. 19, Issue 4, pp. 659-74, (2014) (PubMed).
: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." in: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).
: "Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis." in: The Journal of experimental medicine, Vol. 207, Issue 1, pp. 85-100, (2010) (PubMed).
: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).
: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2." in: American journal of human genetics, Vol. 61, Issue 1, pp. 60-7, (1997) (PubMed).
: "Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2." in: Nature genetics, Vol. 13, Issue 2, pp. 189-95, (1996) (PubMed).
Synonyms and alternative names related to ACVRL1
activin A receptor like type 1 (ACVRL1), activin A receptor type II-like 1 (ACVRL1), activin A receptor like type 1 (acvrl1), activin A receptor like type 1 (Acvrl1), activin A receptor, type II-like 1 (Acvrl1), ACVRL1, ACVRLK1, Acvrlk1, AI115505, AI427544, ALK-1, alk1, ALK1, Alk1, HHT, HHT2, hm:zehn1109, ORW2, R-3, R3, SETHKIR, SKR3, TSR-I, vgb, zehn1109Protein level used designations for ACVRL1
- activin A receptor type II-like 1
- serine/threonine-protein kinase receptor R3
- serine/threonine-protein kinase receptor R3-like
- activin receptor-like kinase 1
- vbg
- violet beauregarde
- TGF-B superfamily receptor type I
- activin A receptor, type II-like kinase 1
- Activin receptor like kinase 1
- SKR3
- TSR-I
- ALK-1
- activin receptor-like kinase-1
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